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Cambridge Past Paper Questions

Browse 23,045questions from 25 years of O-Level & A-Level exams. Click any question to practice.

A-LevelBiologyTransport in plantsMay/June 2025

The diagram shows some root cells. [Figure 28.1 (diagram of root cells with water pathway indicated)] Which statement is correct for the pathway sh...

A-LevelBiologyTransport in plantsMay/June 2025

The graph shows the diameter of a tree trunk at different times. [Figure 29.1 (graph of diameter of tree trunk vs time of day, with points J, K, L)...

A-LevelBiologyTransport in plantsMay/June 2025

The plan diagrams of transverse sections of two plant organs are shown. These are not drawn to scale. [Figure 30.1 (plan diagrams of plant organs w...

A-LevelBiologyImmunityMay/June 2025

The diagrams show three types of blood cells, which are all drawn to the same scale. [Figure 31.1 (diagrams of three blood cells X, Y, Z, with nucl...

A-LevelBiologyGas exchangeMay/June 2025

The graph shows oxygen dissociation curves for three animals. The shape of each curve is influenced by respiration rate and the affinity of haemogl...

A-LevelBiologyTransport in mammalsMay/June 2025

Which statements about a mammalian heart are correct? 1 The right atrium and right ventricle contain deoxygenated blood going to the lungs. 2 The l...

A-LevelBiologyGas exchangeMay/June 2025

How is most carbon dioxide transported in the blood?

A-LevelBiologyGas exchangeMay/June 2025

Which row shows the tissues that are present in the wall of the trachea and the wall of the bronchus?

A-LevelBiologyGas exchangeMay/June 2025

Which factors maintain the diffusion gradient for carbon dioxide at the surface of the alveoli? 1 blood flow around the alveoli 2 breathing movemen...

A-LevelBiologyInfectious diseasesMay/June 2025

A student made notes about two diseases: hand, foot and mouth disease (HFMD) and Lyme disease. HFMD is caused by a viral pathogen and is transmitte...

A-LevelBiologyInfectious diseasesMay/June 2025

Which statements explain why antibiotics may not treat cholera successfully? 1 The infectious organism has developed resistance to the antibiotic. ...

A-LevelBiologyImmunityMay/June 2025

The statements describe the phagocytosis of a bacterium by a macrophage. 1 Digestive enzymes break down the bacterium. 2 Lysosome fuses with the va...

A-LevelBiologyEnzymesMay/June 2025

Amylose and the triglyceride stearin are macromolecules. Students used the enzyme maltase extracted from the fungus Aspergillus oryzae to investiga...

A-LevelBiologyCell structureMay/June 2025

In mammals, the small intestine is the main site of absorption of the products of digestion. Fig. 2.1 is a transmission electron micrograph of a lo...

A-LevelBiologyEnzymesMay/June 2025

Scientists investigated the progress of reactions catalysed by two enzymes: dopa oxidase and neutrase. The reactions catalysed by these enzymes res...

A-LevelBiologyNucleic acids and protein synthesisMay/June 2025

Cells of the immune system have cell surface receptors that detect molecules made by pathogens. One of these cell surface receptors is known as TLR...

A-LevelBiologyTransport in plantsMay/June 2025

Phosphate ions are absorbed from the soil solution by roots and are needed for cellular processes throughout plants. Scientists investigated the mo...

A-LevelBiologyTransport in mammalsMay/June 2025

Fig. 6.1 is a ribbon model of a molecule of haemoglobin. The effect of the partial pressure of oxygen (pO2) and the effect of the partial pressure ...

A-LevelBiologyTransport in plantsMay/June 2025

Root hair cells are specialised plant cells located in the outer layer of young roots of plants. Root hair cells have an essential role in the upta...

A-LevelBiologyBiological moleculesMay/June 2025

The transport of respiratory gases involves blood plasma and red blood cells. Red blood cells contain the globular protein, haemoglobin.

A-LevelBiologyBiological moleculesMay/June 2025

Carrots are root vegetables of the carrot plant. The carrot plant is an important food crop that is grown throughout the world. Carrots have a swee...

A-LevelBiologyInfectious diseasesMay/June 2025

Tuberculosis (TB) is an infectious disease that is caused by a bacterial pathogen. The pathogen has mechanisms to avoid digestion by phagocytes. Ma...

A-LevelBiologyThe mitotic cell cycleMay/June 2025

There is a global shortage of blood for transfusions. Researchers can culture bone marrow stem cells in the laboratory to manufacture red blood cel...

A-LevelBiologyEnzymesMay/June 2025

Horseradish peroxidase (HRP) is an enzyme that can be extracted from the roots of the horseradish plant, Armoracia rusticana. HRP is used extensive...

A-LevelBiologyTransport in plantsMay/June 2025

Ranunculus is a group (genus) of dicotyledonous plants that includes more than 1600 species. (a) Fig. 1.1 is a photomicrograph of a transverse sect...

A-LevelBiologyBiological moleculesMay/June 2025

Bees are insects that produce venom as a means of self-defence. Melittin is a polypeptide present in the venom of bees.

A-LevelBiologyCell structureMay/June 2025

Staphylococcus epidermidis is a species of bacterium that lives on human skin. Staphylococcus aureus is a pathogenic bacterium that can infect humans.

A-LevelBiologyCell membranes and transportMay/June 2025

Lysosomes are membrane-bound organelles found in mammalian cells.

A-LevelBiologyNucleic acids and protein synthesisMay/June 2025

Telomeres are lengths of DNA that consist of repetitive nucleotide sequences. Telomeres are present in eukaryotic chromosomes.

A-LevelBiologyImmunityMay/June 2025

Monoclonal antibodies can be used in the treatment of disease.

A-LevelBiologyEnzymesMay/June 2025

Invertase is an enzyme that catalyses the breakdown of sucrose into glucose and fructose. Invertase can be extracted from yeast cells. You will inv...

A-LevelBiologyCell membranes and transportMay/June 2025

When plant tissue is placed into a solution of sodium chloride, water moves between the sodium chloride solution and the cells in the plant tissue....

A-LevelBiologyCell structureMay/June 2025

L1 is a slide of a stained transverse section through a plant organ. [Figure 2.1] is a diagram of a stage micrometer scale that is being used to ca...

A-LevelBiologyEnergy and respirationMay/June 2025

Organisms need a source of energy for many cellular processes. Respiration involves the release of energy from energy-rich molecules for the synthe...

A-LevelBiologyEnergy and respirationMay/June 2025

A respirometer can be used to investigate how temperature affects the rate of respiration of woodlice. Woodlice are small invertebrate animals. Fig...

A-LevelBiologyInherited changeMay/June 2025

Porphyria is a group of rare genetic diseases in which molecules called porphyrins accumulate in the body. Three examples of porphyria are: • X-lin...

A-LevelBiologyPhotosynthesisMay/June 2025

Scientists have invented a way of producing food by artificial photosynthesis. • Solar panels convert sunlight energy into electricity. • The elect...

A-LevelBiologySelection and evolutionMay/June 2025

The Galápagos is a group of islands with a high biodiversity.

A-LevelBiologyHomeostasisMay/June 2025

In the kidney, various molecules move between the blood and the kidney nephron. Table 6.1 describes the movements of molecules at three regions of ...

A-LevelBiologyHomeostasisMay/June 2025

Insulin is an example of a cell-signalling molecule of the endocrine system.

A-LevelBiologyControl and coordinationMay/June 2025

The presence of gibberellins in a plant cell leads to the expression of genes involved in stem elongation. Describe how gibberellin causes stem elo...

A-LevelBiologyBiodiversity and conservationMay/June 2025

A species is classified into one of three domains.

A-LevelBiologyControl and coordinationMay/June 2025

During the course of an action potential, the potential difference across a neurone membrane changes. Table 10.1 shows the potential difference acr...

A-LevelBiologyEnergy and respirationMay/June 2025

Fig. 1.1 is a diagram of part of the inner membrane of a mitochondrion. [Figure 1.1]

A-LevelBiologySelection and evolutionMay/June 2025

When organisms reproduce, they pass on their alleles to the next generation. There are many factors that can affect how allele frequencies change o...

A-LevelBiologyInherited changeMay/June 2025

Rice, Oryza sativa, is an important grain crop. A rice grain is a seed and can have a structure known as an awn, which projects from the tip of the...

A-LevelBiologyInherited changeMay/June 2025

Sexual reproduction in plants and animals involves: the formation of gametes as a result of meiosis the process of fertilisation.

A-LevelBiologyGenetic technologyMay/June 2025

A number of diseases in humans can be treated using recombinant human proteins. These are produced by recombinant DNA technology.

A-LevelBiologyTransport in plantsMay/June 2025

Guard cells are located in the epidermis of the leaves of most plants. When environmental conditions change, this causes changes in guard cells tha...

A-LevelBiologyControl and coordinationMay/June 2025

An axon membrane is described as being at its resting potential when an action potential is not occurring.

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