In mammals, the small intestine is the main site of absorption of the products of digestion. Fig. 2.1 is a transmission electron micrograph of a longitudinal section (L.S.) of part of an epithelial cell from the small intestine of a mammal. Fig. 2.2 is a transmission electron micrograph of a horizontal section made at the position indicated by the two arrows in Fig. 2.1. [Figure 2.1] [Figure 2.2]
- (a)Microvilli and cilia are cell structures. Describe how the structure of cilia differs from the structure of the microvilli visible in Fig. 2.1 and Fig. 2.2.[2]
- (b)A scientist measured the length and the diameter of some of the microvilli shown in Fig. 2.1 to estimate the total surface area of microvilli on the surface of the epithelial cell. The scientist assumed that each microvillus was cylindrical in shape. Suggest one other measurement needed to estimate the total surface area of the microvilli of the epithelial cell.[1]
- (c)Identify the organelle labelled Z in Fig. 2.1 and explain why there is a large number of these organelles in the epithelial cells of the small intestine. organelle explanation[2]
- (d)Bacteria are found attached to epithelial cells in the intestines of mammals. Describe how the organisation and distribution of DNA in epithelial cells differs from the organisation and distribution of DNA in bacterial cells.[2]
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Mark scheme
Marking points from the official mark scheme (May/June 2025). The mark or mark type is shown in brackets.
- [1] (a) (composed of) microtubules / not composed of microfilaments / not composed of actin (fibres) ; R if microvilli have microtubules
- [1] (a) 9+2, arrangement / pattern / structure (in horizontal section) ;
- [1] (a) AVP; e.g. ref. to component proteins – e.g. tubulin / dynein
- [1] (a) (cilia) extend from / attach to, a basal body / basal body at base R centrioles
- [1] (b) number of microvilli (over the surface of the cell) ; I amount/quantity
- [1] (c) mitochondrion ;
- [1] (c) synthesises / makes / produces / provides, ATP for, active transport/active uptake / endocytosis / exocytosis; I absorption A provides energy if no ATP A any other suitable function of an epithelial cell in the small intestine e.g. synthesis of, enzymes / carrier proteins / mucus or movement of organelles within cell
- [1] (d) organisation for one mark linear, chromosome / DNA A straight or DNA associated with, histones / histone proteins / basic proteins; A ref. to chromatin
- [1] (d) distribution for one mark DNA, contained in nucleus / surrounded by nuclear envelope / surrounded by nuclear membranes ; A ref. to DNA in nucleolus
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