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A-LevelBiologyTransport in mammalsMay/June 2025Paper 2 Q612 Marks

Fig. 6.1 is a ribbon model of a molecule of haemoglobin. The effect of the partial pressure of oxygen (pO2) and the effect of the partial pressure of carbon dioxide (pCO2) on the percentage saturation of haemoglobin was investigated. A sample of mammalian blood was exposed to a gas mixture that contained increasing pO2. In the experiment, the pCO2 was maintained at 2.7kPa. The percentage saturation of haemoglobin in the blood sample was determined as the pO2 increased. The experiment was repeated with further samples of blood with a pCO2 maintained at 5.3 kPa and at 10.7 kPa. The results are shown in Fig. 6.2. [Figure 6.1] [Figure 6.2]

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About This A-Level Biology Question

This structured question appeared in the Cambridge A-Level Biology (9700) May/June 2025 examination, Paper 2 Variant 1. It tests the topic of Transport in mammals and is worth 12 marks.

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