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Cambridge Past Paper Questions

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A-LevelBiologyNucleic acids and protein synthesisFeb/Mar 2024

During the mitotic cell cycle, the chromosomal DNA is replicated. The specific points in DNA molecules where replication is occurring are known as ...

A-LevelBiologyNucleic acids and protein synthesisFeb/Mar 2024

Which molecule has its synthesis directly controlled by DNA?

A-LevelBiologyTransport in plantsFeb/Mar 2024

Which statement correctly describes the association between a companion cell and its sieve tube cell?

A-LevelBiologyTransport in plantsFeb/Mar 2024

A maize seedling was grown in soil that contained lanthanum ions labelled with a chemical that fluoresces under ultraviolet light. The diagram repr...

A-LevelBiologyTransport in plantsFeb/Mar 2024

Which description of adhesion and cohesion is correct?

A-LevelBiologyTransport in plantsFeb/Mar 2024

Which conditions are needed to allow the mass flow of sucrose in phloem sieve tubes?

A-LevelBiologyTransport in mammalsFeb/Mar 2024

One type of congenital heart defect is where the left and right atria are not completely separated. This is called an atrial septal defect (ASD). A...

A-LevelBiologyBiological moleculesFeb/Mar 2024

Which property of water, related to its role in blood and tissue fluid, is correctly described?

A-LevelBiologyTransport in mammalsFeb/Mar 2024

Which statement about tissue fluid formation is correct?

A-LevelBiologyGas exchangeFeb/Mar 2024

Oxyhaemoglobin, carbaminohaemoglobin, haemoglobinic acid and carbonic anhydrase are found inside red blood cells. How many of these substances will...

A-LevelBiologyGas exchangeFeb/Mar 2024

Which of these structures typically contain cartilage and cilia? 1 bronchi 2 bronchioles 3 trachea

A-LevelBiologyGas exchangeFeb/Mar 2024

Which statements about the function of tissues found in the human gas exchange system are correct? 1 Collagen in the bronchi prevents them collapsi...

A-LevelBiologyInfectious diseasesFeb/Mar 2024

Antibiotic-resistant strains of Mycobacterium tuberculosis are a major problem when treating TB. A new antibiotic, teixobactin, could be very effec...

A-LevelBiologyImmunityFeb/Mar 2024

Monoclonal antibodies are now being used to treat some human diseases. What explains why monoclonal antibodies are suitable for this purpose? 1 The...

A-LevelBiologyImmunityFeb/Mar 2024

Measles is an infectious disease caused by a virus. The graph shows the number of cases of measles each year in a country before and after a vaccin...

A-LevelBiologyCell membranes and transportFeb/Mar 2024

A-LevelBiologyImmunityFeb/Mar 2024

A-LevelBiologyTransport in plantsFeb/Mar 2024

A-LevelBiologyNucleic acids and protein synthesisFeb/Mar 2024

A-LevelBiologyInfectious diseasesFeb/Mar 2024

The pathogen that causes cholera is a prokaryote.

A-LevelBiologyImmunityFeb/Mar 2024

Fig. 6.1 is a simplified diagram representing a section through the human immunodeficiency virus (HIV) particle that causes HIV/AIDS. The diagram s...

A-LevelBiologyEnzymesFeb/Mar 2024

Seeds of many plant species contain an enzyme that is used to hydrolyse sucrose into reducing sugars. This enzyme is essential to provide the reduc...

A-LevelBiologyCell structureFeb/Mar 2024

P1 is a slide of a stained transverse section through a plant leaf. (b) Fig. 2.1 is a photomicrograph of a transverse section through a leaf of a d...

A-LevelBiologyHomeostasisFeb/Mar 2024

Fig. 1.1 is a diagram of a nephron. [Figure 1.1]

A-LevelBiologyInherited changeFeb/Mar 2024

The scientist Gregor Mendel investigated differences in the length of the stem in the pea plant, Pisum sativum. In 1866, he published the results o...

A-LevelBiologyInherited changeFeb/Mar 2024

Cystic fibrosis is an autosomal recessive genetic disease. People with cystic fibrosis have a homozygous recessive genotype.

A-LevelBiologyHomeostasisFeb/Mar 2024

Holstein Friesian cattle are a breed of cattle used by dairy farmers in many countries of the world for the high milk yield of their cows. [Figure ...

A-LevelBiologySelection and evolutionFeb/Mar 2024

Complete the following paragraphs using the most appropriate word or words. The theory of evolution describes a process that can lead to the format...

A-LevelBiologyEnergy and respirationFeb/Mar 2024

A respirometer is a piece of apparatus that can be used to measure the rate of respiration of living tissue such as germinating peas. A simple resp...

A-LevelBiologyPhotosynthesisFeb/Mar 2024

The light-dependent stage of photosynthesis occurs within chloroplasts. In this stage, electrons are emitted from the chlorophyll a molecules and p...

A-LevelBiologyInfectious diseasesFeb/Mar 2024

Approximately 2 × 10⁹ people in the world are currently infected with the bacterial disease tuberculosis (TB) caused by Mycobacterium tuberculosis....

A-LevelBiologyControl and coordinationFeb/Mar 2024

An investigation was carried out to study the effect of different intensities of blue light on the percentage germination of barley seeds. Barley s...

A-LevelBiologyControl and coordinationFeb/Mar 2024

Striated muscle is composed of myofibrils. Myofibrils contain several structural proteins including troponin, tropomyosin, actin and myosin.

A-LevelBiologyCell membranes and transportFeb/Mar 2024

Onions are vegetables that are harvested from the plant Allium cepa. In many countries, small onions are used to make pickled onions. Pickled onion...

A-LevelBiologyInherited changeFeb/Mar 2024

Drosophila melanogaster is a small fruit fly that is often used in research on genetics. Wild fruit flies normally have dark red eyes due to the pr...

A-LevelBiologyCell structureFeb/Mar 2025

In an electron micrograph, the length of a mitochondrion is measured as 17.1cm. The magnification of the electron micrograph is ×38000. What is the...

A-LevelBiologyCell structureFeb/Mar 2025

There is a theory that mitochondria and chloroplasts were originally free-living prokaryotes. It is thought that millions of years ago these free-l...

A-LevelBiologyCell structureFeb/Mar 2025

Which row correctly describes a function of each cell structure?

A-LevelBiologyCell structureFeb/Mar 2025

Which cell components are present in typical prokaryotic cells?

A-LevelBiologyCell structureFeb/Mar 2025

X-ray analysis of fossilised cells found in rocks in central India dating back 1.6 billion years has revealed several features. 1 The cells are up ...

A-LevelBiologyCell structureFeb/Mar 2025

The electron micrograph shows an organelle found in some cells of many multicellular organisms. [Figure 6.1] Which row shows structures that are ex...

A-LevelBiologyBiological moleculesFeb/Mar 2025

What could take place during a hydrolysis reaction? 1 A glycosidic bond is broken. 2 A molecule of water is produced. 3 A sucrose molecule is split...

A-LevelBiologyBiological moleculesFeb/Mar 2025

Hydroxyproline is synthesised by addition of an –OH group to the R-group of the amino acid proline. Hydroxyproline is a major component of collagen...

A-LevelBiologyBiological moleculesFeb/Mar 2025

Plant cell walls are strengthened by cellulose molecules that are arranged in several layers. Within each layer, the cellulose molecules are arrang...

A-LevelBiologyBiological moleculesFeb/Mar 2025

Galactogen is a storage polysaccharide in some animal species. It is a branched polymer that is formed from ẞ-galactose monomers. Which comparison ...

A-LevelBiologyEnzymesFeb/Mar 2025

Which levels of protein structure are always involved in forming the active site of an enzyme?

A-LevelBiologyEnzymesFeb/Mar 2025

Catalase is an enzyme that breaks down hydrogen peroxide into water and oxygen. Catalase was added to a solution of hydrogen peroxide and the oxyge...

A-LevelBiologyEnzymesFeb/Mar 2025

Succinic dehydrogenase is an enzyme that catalyses the conversion of succinate to fumarate in aerobic respiration. Malonate is a reversible inhibit...

A-LevelBiologyCell membranes and transportFeb/Mar 2025

The diagram shows the dimensions of two blocks of agar. The diagram has been drawn to scale. [Figure 16.1] The blocks of agar were stained pink wit...

A-LevelBiologyCell membranes and transportFeb/Mar 2025

The graph shows how the rate of facilitated diffusion of substance X across a cell surface membrane changed as the concentration of substance X inc...

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