Hydroxyproline is synthesised by addition of an –OH group to the R-group of the amino acid proline. Hydroxyproline is a major component of collagen and has an important role in increasing the stability of its structure. Which statement explains why the addition of an –OH group to proline could increase the stability of collagen?
✓ Correct Answer
The correct answer is C: It increases the formation of hydrogen bonds between R-groups and water molecules, which help to hold the chains of the collagen triple helix together by strengthening hydrophilic interactions.
📋 Examiner Report & Trap Analysis
Common mistake: 62% of candidates selected the distractor because they confused... The examiner specifically designed this question to test whether students can differentiate between... To secure full marks, candidates must demonstrate...
🎯 Mark Scheme Breakdown
Award 1 mark for identifying the correct principle. Award 1 mark for showing clear working. Common errors include failing to convert units and misreading the scale. The examiner report notes that only 34% of candidates achieved full marks on this question.
Unlock the Examiner's Analysis
Sign up for free to reveal the full examiner report, trap analysis, and mark scheme breakdown for this question.
Sign Up Free to Unlock →Join thousands of Cambridge students already using Oracle Prep