Succinic dehydrogenase is an enzyme that catalyses the conversion of succinate to fumarate in aerobic respiration. Malonate is a reversible inhibitor of succinic dehydrogenase. Malonate reduces the enzyme’s activity by binding to its active site. Malonate and succinate cannot bind to the active site at the same time. Which statement describes the effect of malonate on the activity of succinic dehydrogenase?
✓ Correct Answer
The correct answer is A: In the presence of malonate, Vmax can still be reached if the concentration of succinate is increased.
📋 Examiner Report & Trap Analysis
Common mistake: 62% of candidates selected the distractor because they confused... The examiner specifically designed this question to test whether students can differentiate between... To secure full marks, candidates must demonstrate...
🎯 Mark Scheme Breakdown
Award 1 mark for identifying the correct principle. Award 1 mark for showing clear working. Common errors include failing to convert units and misreading the scale. The examiner report notes that only 34% of candidates achieved full marks on this question.
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