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A-LevelBiologyNucleic acids and protein synthesis9700/12 · Feb/Mar 2024 · Q261 Mark

During the mitotic cell cycle, the chromosomal DNA is replicated. The specific points in DNA molecules where replication is occurring are known as replication forks. A typical human chromosome has about 150 million base pairs of DNA. It takes about 1 hour to replicate the DNA of a typical human chromosome. The rate of replication using a single replication fork is approximately 50 base pairs per second. Approximately how many replication forks must occur in a typical human chromosome during DNA replication?

A835
B41 700
C50 000
D3 000 000

✓ Correct answer

A: 835

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Topic
Nucleic acids and protein synthesis, A-Level Biology (syllabus 9700). Multiple choice, 1 mark.
Source
A-Level Biology, Feb/Mar 2024 Paper 1 Variant 2, question 26.

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