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Cambridge Past Paper Questions

Browse 23,045questions from 25 years of O-Level & A-Level exams. Click any question to practice.

A-LevelBiologyInherited changeMay/June 2024

The gene BRCA1 is expressed in breast tissue and in several other tissues of the body. BRCA1 codes for a tumour suppressor protein. This protein is...

A-LevelBiologyEnergy and respirationMay/June 2024

[Figure 6.1] is a diagram of part of a mitochondrion.

A-LevelBiologyPhotosynthesisMay/June 2024

A student investigated the effect of temperature on the rate of photosynthesis at two different light intensities. The rate of photosynthesis was d...

A-LevelBiologyControl and coordinationMay/June 2024

[Figure 8.1] is a diagram of a sensory neurone.

A-LevelBiologyBiodiversity and conservationMay/June 2024

The Asian common toad, Duttaphrynus melanostictus, arrived accidentally in eastern Madagascar in 2010 on a ship. [Figure 9.1] shows an Asian common...

A-LevelBiologyHomeostasisMay/June 2024

In mammals, blood glucose concentration is maintained around a set point so that the mammal can function efficiently. This is an example of homeost...

A-LevelBiologyHomeostasisMay/June 2024

Fig. 1.1 outlines the effect of antidiuretic hormone (ADH) on the cells of the collecting duct. The cell-signalling mechanism of ADH is similar to ...

A-LevelBiologyInherited changeMay/June 2024

Phenotypic variation exists in many forms. (a) Some examples of phenotypic variation in plants and animals are described in Table 2.1. Complete Tab...

A-LevelBiologyInherited changeMay/June 2024

In plants and humans, the phenotype of an organism is determined by the genotype and the environment. (a) Plants from the genus Primula have differ...

A-LevelBiologyGenetic technologyMay/June 2024

Genetic engineering is a technique used to modify the genetic material of a specific organism to change a characteristic.

A-LevelBiologyInherited changeMay/June 2024

BRCA2 is a tumour-suppressor gene. Its gene product, BRCA2, is involved in DNA repair. If the DNA cannot be repaired, BRCA2 has a role in causing t...

A-LevelBiologyTransport in plantsMay/June 2024

A-LevelBiologyPhotosynthesisMay/June 2024

(a) Experiments were carried out to determine the effect of light intensity on the rate of photosynthesis of a species of the unicellular protoctis...

A-LevelBiologyEnergy and respirationMay/June 2024

(a) Fig. 8.1 is a diagram of a mitochondrion. [Figure 8.1]

A-LevelBiologyBiodiversity and conservationMay/June 2024

(a) Fig. 9.1 shows how the mean global atmospheric carbon dioxide concentration has changed over the 800000 (800 ×103) years leading up to the year...

A-LevelBiologyControl and coordinationMay/June 2024

(a) Fig. 10.1 is a diagram of part of a neurone membrane while the resting potential is maintained. [Figure 10.1]

A-LevelBiologyTransport in plantsMay/June 2024

A student investigated the effect of wind speed on the rate of transpiration. The student used the flowering plant Japanese spiraea, Spiraea japoni...

A-LevelBiologyTransport in plantsMay/June 2024

The responses of plant species to water stress can be classified as either isohydric or anisohydric. • Isohydric plant species close stomata during...

A-LevelBiologyInfectious diseasesMay/June 2024

Female mosquitoes feed on human blood. Some species of mosquitoes are vectors of human pathogens. For example, female mosquitoes of the species Aed...

A-LevelBiologyBiodiversity and conservationMay/June 2024

Tree plantations are areas where trees are planted for a particular purpose. Some tree plantations increase the supply of wood for construction and...

A-LevelBiologyCell structureMay/June 2024

Tumours may be described as benign or malignant. Malignant tumours can lead to greater complications for the person with the tumour. Early identif...

A-LevelBiologyTransport in mammalsMay/June 2024

Blood vessels must be able to withstand and maintain varying blood pressures. There are several methods that could be used to determine the strengt...

A-LevelBiologyControl and coordinationMay/June 2024

Gibberellins are a group of plant hormones that are involved in the elongation of plant stems. A student investigated the effect of two different c...

A-LevelBiologyCell structureMay/June 2025

Which row shows possible uses of an eyepiece graticule?

A-LevelBiologyCell structureMay/June 2025

Which statement about a light microscope is correct?

A-LevelBiologyCell structureMay/June 2025

The electron micrograph shows a cell. [Electron micrograph of a cell] What is the actual maximum length of the cell?

A-LevelBiologyCell structureMay/June 2025

The table compares some biochemical molecules of P, Q, R and S. Which row correctly identifies P, Q, R and S?

A-LevelBiologyCell structureMay/June 2025

Which cell structures contain enzymes and are enclosed by a double membrane? 1 nucleus 2 mitochondrion 3 chloroplast

A-LevelBiologyCell structureMay/June 2025

What is the order of size of cell structures?

A-LevelBiologyBiological moleculesMay/June 2025

A sample of a solution of sucrose tested for reducing sugars remains blue, but when another sample of the same solution is tested for non-reducing ...

A-LevelBiologyBiological moleculesMay/June 2025

Which molecules contain at least two double bonds? [Figure 8.1 (Venn diagram showing circles for collagen, saturated triglyceride, haemoglobin, wit...

A-LevelBiologyBiological moleculesMay/June 2025

Amylose, amylopectin and glycogen are all polysaccharides. Enzyme X removes one maltose molecule at a time from the ends of a polysaccharide molecu...

A-LevelBiologyBiological moleculesMay/June 2025

Which property of water enables sweating to be an efficient means of losing heat from the body?

A-LevelBiologyBiological moleculesMay/June 2025

Which bonds are found in the levels of structure of a protein molecule?

A-LevelBiologyEnzymesMay/June 2025

Prokaryotes and eukaryotes use extracellular enzymes. Extracellular digestive enzymes are found in the external environments of some prokaryotes. S...

A-LevelBiologyEnzymesMay/June 2025

Amylase breaks down starch molecules. Which substance will have the same number of molecules for the duration of this reaction?

A-LevelBiologyEnzymesMay/June 2025

Which graphs could show the effect of pH on the rate of enzyme-catalysed reactions? [Figure 14.1 (four graphs of rate of reaction vs pH)]

A-LevelBiologyEnzymesMay/June 2025

After a heart attack, the enzyme lactate dehydrogenase leaks into the blood plasma from damaged heart muscle. What is required to measure the activ...

A-LevelBiologyEnzymesMay/June 2025

Which graph correctly shows Km and Vmax? [Figure 16.1 (four graphs showing rate of reaction vs concentration, with Vmax and Km indicated)]

A-LevelBiologyCell membranes and transportMay/June 2025

Cell membranes become less fluid as the temperature decreases. Bacteria and yeast cannot regulate their cell temperatures. How do bacteria and yeas...

A-LevelBiologyCell membranes and transportMay/June 2025

Samples X, Y and Z are epidermal tissues cut from an onion. Each epidermal tissue was immersed in one of three different concentrations of a salt s...

A-LevelBiologyCell membranes and transportMay/June 2025

The graph shows the results of an osmosis investigation using potato tissue. [Figure 19.1 (graph of percentage change in mass vs concentration of s...

A-LevelBiologyCell membranes and transportMay/June 2025

Some agar was coloured pink using a pH indicator. The pink agar was then used to make three agar cubes with different dimensions. [Figure 20.1 (thr...

A-LevelBiologyThe mitotic cell cycleMay/June 2025

The diagram shows the arrangement of chromosomes with attached spindle fibres during a stage of mitosis. [Figure 21.1 (diagram of chromosomes with ...

A-LevelBiologyThe mitotic cell cycleMay/June 2025

During which phase of the cell cycle does DNA replication take place?

A-LevelBiologyThe mitotic cell cycleMay/June 2025

Human body cells in interphase have 46 chromosomes. What is correct about the number of telomeres present in prophase of a human body cell?

A-LevelBiologyNucleic acids and protein synthesisMay/June 2025

Sometimes hydrogen bonds form temporarily between the bases of two strands of RNA. How many hydrogen bonds form when guanine and uracil each bind t...

A-LevelBiologyNucleic acids and protein synthesisMay/June 2025

The table shows all the possible DNA triplet codes for some amino acids. amino acid: cysteine, DNA triplet code: ACA amino acid: cysteine, DNA trip...

A-LevelBiologyTransport in plantsMay/June 2025

Which row is correct for transpiration?

A-LevelBiologyTransport in plantsMay/June 2025

Which features of companion cells and xylem vessel elements make them suitable for their function?

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