Blood vessels must be able to withstand and maintain varying blood pressures. There are several methods that could be used to determine the strength of a blood vessel. One method is called the circumferential tensile strength (CTS) test, as shown in Fig. 1.1. [Figure 1.1] The ring of blood vessel, shown in Fig. 1.1, was cut from a length of artery or vein that was prepared by removing surrounding tissues. A student wanted to use the apparatus in Fig. 1.1 to determine the mass needed to break an artery and the mass needed to break a vein.
- (a)(i)Identify the independent variable and the dependent variable in this investigation. independent variable dependent variable [1]
- (a)(ii)The student was provided with lengths of a large artery, lengths of a large vein and standard laboratory apparatus. Describe how the student could use the CTS test to determine the mass needed to break an artery and the mass needed to break a vein. Your method should be set out in a logical order and be detailed enough to let another person follow it.[6]
- (b)(i)Complete Table 1.1 by calculating the percentage increase in length of the ring of vein for 10g, 40 g and 50 g.[2]
- (b)(ii)Explain why the student calculated the percentage increase in length of the ring of vein.[1]
- (b)(iii)On the grid in Fig. 1.3, plot a graph of the data shown in Table 1.1. [Figure 1.3][3]
- (b)(iv)The student carried out the same investigation using a muscular artery instead of a vein. Predict the shape of the curve you would expect for the muscular artery. On Fig. 1.3: • sketch the curve you predicted for the muscular artery • label this curve with the word artery.[2]
- (b)(v)Explain the shape of the curve you sketched for the muscular artery in Fig. 1.3.[2]
- (b)(vi)Another student suggested that the experiment should be repeated with more rings from the same blood vessels. Suggest two other ways the student could modify the method to improve the quality of the results.[2]
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Mark scheme
Marking points from the official mark scheme (May/June 2024). The mark or mark type is shown in brackets.
- [1] independent variable type of blood vessel / artery and vein and dependent variable mass required to break (the blood vessel);
- [6] any six from: 1 method to cut the blood vessel ; 2 method to measure blood vessel of, same / stated, length / AW ; 3 idea of discard samples that are damaged ; 4 idea of waiting (to see if the blood vessel breaks) before adding the next (10g) mass ; 5 use, artery and vein / blood vessels, from the same source ; 6 add (10 g) masses, to the mass hanger, until the blood vessel breaks ; 7 idea of measuring mass of mass hanger / including mass of mass hanger; 8 for each type of blood vessel, measure / note / record / AW, (total) mass when the blood vessel broke; 9 use at least three measurements for each type of blood vessel and calculate a mean ; 10 safety comment with hazard and precaution; hazard: knife / scalpel, risk: injury, precaution: cut away from hand hazard: blood vessels, risk: biohazard / pathogens / allergy, precaution: gloves / mask / PPE / use disinfectant / wash hands hazard: mass hanger falling, risk: injury, precaution: suitable precaution to prevent injury 11 idea of repeat procedure with smaller mass intervals near to breaking mass;
- [2] three values correct ;; one or two correct max 1 (10g: 71, 40g: 95, 50g: 95)
- [1] 1 to make a valid comparison (with other blood vessels / veins) ; 2 allows comparison as, initial / starting, length (of veins) is, not constant / AW;
- [3] 1 correct orientation for axes and linear scale ; 2 axes labelled and units; 3 all points plotted correctly and line drawn accurately;
- [2] 1 curve for artery starts at same point as the vein ; 2 curve for artery below curve for vein and does not intersect ;
- [2] any two from: 1 starts at, same point/origin, as using percentage increase ; 2 (muscular) arteries have a thicker, wall / tunica media / muscle layer (than the vein) or 3 (muscular) arteries have more (smooth) muscle (than the vein) ; 4 idea of (muscular artery) withstands more (blood) pressure so stretches less (than the vein);
- [2] any two from: 1 use smaller mass intervals ; 2 extend the range of the masses added ; 3 use a, force meter / Newton meter / data logger/AW, (to apply force); 4 attach a, pointer / fiducial mark, to the ring of blood vessel (to improve length measurement / removing parallax) ; 5 use, same / stated, width of blood vessel ;
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