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Cambridge & Pearson Edexcel Past Paper Questions

Browse 35,704 questions from Cambridge O-Level & A-Level and Pearson Edexcel IGCSE & IAL exams. Click any question to practice.

A-LevelBiologyGas exchangeOct/Nov 2025

The photomicrograph shows the wall of a bronchus as seen with a light microscope. [Photomicrograph of the wall of a bronchus with labels X, Y, Z] W...

A-LevelBiologyInfectious diseasesOct/Nov 2025

Which factors affect the global pattern of distribution of malaria? 1 the disease is mainly restricted to tropical and subtropical environments 2 t...

A-LevelBiologyImmunityOct/Nov 2025

Which molecule could be a self antigen?

A-LevelBiologyImmunityOct/Nov 2025

The diagram shows an antibody molecule with some parts labelled. [Diagram of an antibody molecule with parts P, W, V, U, R, S, T labelled] Which ro...

A-LevelBiologyCell membranes and transportOct/Nov 2025

Fig. 1.1 shows a diagram of the fluid mosaic model of the structure of the cell surface membrane.

A-LevelBiologyTransport in mammalsOct/Nov 2025

Haemoglobin is a globular protein containing haem groups. Explain how the presence of haem groups allows the haemoglobin molecule to transport oxygen.

A-LevelBiologyEnzymesOct/Nov 2025

The lock-and-key hypothesis and the induced-fit hypothesis are used to describe the interaction of enzymes and their substrates. Describe one simil...

A-LevelBiologyBiological moleculesOct/Nov 2025

Fig. 4.1 is a photomicrograph of a copepod. These animals are found living in sea water and in fresh water environments.

A-LevelBiologyTransport in plantsOct/Nov 2025

Fig. 5.1 is a photomicrograph of a longitudinal section through part of the stem of a plant.

A-LevelBiologyNucleic acids and protein synthesisOct/Nov 2025

Alveolar macrophages are phagocytes found in the human gas exchange system. They produce hydrolytic enzymes, such as lysozyme, to digest pathogens ...

A-LevelBiologyCell structureOct/Nov 2025

The wall of the small intestine is highly folded to form villi. Between the villi are infoldings known as crypts of Lieberkühn. Fig. 1.1 is a diagr...

A-LevelBiologyInfectious diseasesOct/Nov 2025

Cholera is an infectious intestinal disease caused by a bacterial pathogen.

A-LevelBiologyNucleic acids and protein synthesisOct/Nov 2025

The gene LCT codes for the enzyme lactase. In babies, lactase synthesis is necessary for digesting lactose, the sugar found in milk. Another gene, ...

A-LevelBiologyCell membranes and transportOct/Nov 2025

Bacteria can be classified according to the type of cell wall they have. Gram-negative bacteria have a cell wall with an outer layer known as the o...

A-LevelBiologyTransport in plantsOct/Nov 2025

A plant that is described as a mesophyte has evolved to grow in conditions that do not normally experience water stress (low availability of water)...

A-LevelBiologyTransport in mammalsOct/Nov 2025

In the pulmonary circulation of a mammal, deoxygenated blood becomes oxygenated when red blood cells pass through alveolar capillaries and haemoglo...

A-LevelBiologyCell membranes and transportOct/Nov 2025

Many substances can move through cell surface membranes between the cytoplasm of animal cells and the extracellular environment. (a) A student made...

A-LevelBiologyBiological moleculesOct/Nov 2025

Collagen is a fibrous protein found in many tissues in animals. Fig. 2.1 shows the composition of a collagen fibre.

A-LevelBiologyEnzymesOct/Nov 2025

(a) Describe the induced-fit hypothesis of enzyme action. (b) Many marine organisms can become attached to hard surfaces such as rocks or the surfa...

A-LevelBiologyNucleic acids and protein synthesisOct/Nov 2025

(a) Fig. 4.1 shows a phosphorylated nucleotide which is one of the monomers that is used to synthesise DNA during replication. (b) Fig. 4.2 shows a...

A-LevelBiologyNucleic acids and protein synthesisOct/Nov 2025

Inhibitors are substances that prevent biological processes in a variety of different ways. Table 5.1 shows some antibiotics, their modes of action...

A-LevelBiologyTransport in mammalsOct/Nov 2025

(a) A student studied the structure of a mammalian heart. The student took a photograph of the left side of a dissected heart as shown in Fig. 6.1....

A-LevelBiologyInfectious diseasesOct/Nov 2025

The bacterium Streptococcus pneumoniae is commonly found in the throat. S. pneumoniae produces hydrogen peroxide as it grows. A sample can be taken...

A-LevelBiologyCell membranes and transportOct/Nov 2025

Dialysis tubing is a partially permeable membrane. Glucose molecules can diffuse through the dialysis tubing. You are required to investigate the d...

A-LevelBiologyTransport in plantsOct/Nov 2025

K1 is a slide of a stained transverse section through a root.

A-LevelBiologyInherited changeOct/Nov 2025

Guinea pigs, Cavia porcellus, vary in the length and colour of their fur. Fig. 1.1 shows a guinea pig with short black fur. [Figure 1.1] Two genes ...

A-LevelBiologyBiodiversity and conservationOct/Nov 2025

Exserohilum turcicum is a fungal pathogen. The growth of the mycelium of the fungus damages the leaves of maize plants, Zea mays. Leaf damage reduc...

A-LevelBiologyPhotosynthesisOct/Nov 2025

Plants have several different photosynthetic pigments in their chloroplasts. (a) A student separated and identified the chloroplast pigments presen...

A-LevelBiologySelection and evolutionOct/Nov 2025

The wolf, Canis lupus, lives in North America. Wolves may have a grey or a black coat colour. The colour of an individual wolf depends on the DNA i...

A-LevelBiologyControl and coordinationOct/Nov 2025

The endocrine system and the nervous system both coordinate responses in mammals. (a) Complete Table 5.1 to show the features of three cell-signall...

A-LevelBiologyBiodiversity and conservationOct/Nov 2025

The distribution of the large blue butterfly, Phengaris arion, extends across Europe and Asia. It is assessed by the International Union for Conser...

A-LevelBiologyEnergy and respirationOct/Nov 2025

In aerobic respiration, most ATP is produced by oxidative phosphorylation. (a) Outline the features of ATP that make it suitable as the universal e...

A-LevelBiologyGenetic technologyOct/Nov 2025

LibertyLink® soybean is a genetically modified crop. It was first grown in 1996 and used in food products from 1998. It has been grown in 6 countri...

A-LevelBiologyHomeostasisOct/Nov 2025

(a) Fig. 9.1 shows a longitudinal section of a human kidney. [Figure 9.1] Name the regions of the kidney labelled X and Y in Fig. 9.1. X Y (b) A bi...

A-LevelBiologyNucleic acids and protein synthesisOct/Nov 2025

Explain the relationship between genes, proteins and phenotype, with reference to two examples of genetic diseases in humans.

A-LevelBiologyTransport in plantsOct/Nov 2025

Rice, Oryza sativa, is a crop plant that has adapted to grow in flooded fields. Fig. 1.1 outlines the effects on rice plants of growing in flooded ...

A-LevelBiologyInherited changeOct/Nov 2025

Explain the terms gene, genotype and phenotype. gene genotype phenotype

A-LevelBiologyNucleic acids and protein synthesisOct/Nov 2025

The lac operon is present in the genome of the bacterium Escherichia coli. When glucose is not available, the presence of lactose in the extracellu...

A-LevelBiologySelection and evolutionOct/Nov 2025

The evolution of antibiotic resistance in bacteria has occurred as a result of natural selection.

A-LevelBiologyGenetic technologyOct/Nov 2025

Metachromatic leukodystrophy (MLD) is a genetic disease that affects the nervous system. MLD is caused by mutations in the ARSA gene located on chr...

A-LevelBiologyHomeostasisOct/Nov 2025

Phosphoinositide 3-kinase (PI3K) and protein kinase B (PKB) are enzymes involved in the regulation of blood glucose concentration. Fig. 6.1 shows a...

A-LevelBiologyControl and coordinationOct/Nov 2025

The Venus fly trap, Dionaea muscipula, is a plant that can capture insects. Each leaf of a Venus fly trap is modified to form 2 lobes. Fig. 7.1 sho...

A-LevelBiologyBiodiversity and conservationOct/Nov 2025

Palm oil is the most widely used vegetable oil. It is obtained from the African oil palm, Elaeis guineensis. Oil palms are the highest yielding veg...

A-LevelBiologyPhotosynthesisOct/Nov 2025

Fig. 9.1 shows an absorption spectrum for chlorophyll a and the corresponding action spectrum for a species of plant. Explain what is meant by an a...

A-LevelBiologyControl and coordinationOct/Nov 2025

Nerve impulses can be transmitted along a myelinated motor neurone to a neuromuscular junction at fast speeds of up to 100ms⁻¹. Outline how a trans...

A-LevelBiologyControl and coordinationOct/Nov 2025

The endocrine system and the nervous system both coordinate responses in mammals.

A-LevelBiologyEnergy and respirationOct/Nov 2025

In aerobic respiration, most ATP is produced by oxidative phosphorylation.

A-LevelBiologyHomeostasisOct/Nov 2025

Fig. 9.1 shows a longitudinal section of a human kidney.

A-LevelBiologyControl and coordinationOct/Nov 2025

Juglone is a chemical produced by plants in the genus Juglans, which includes different species of walnut tree. Fig. 1.1 shows a black walnut tree....

A-LevelBiologyInfectious diseasesOct/Nov 2025

Compounds containing nitrite ions (NO₂⁻) are present in many foods eaten by humans. Scientists tested the effect of different concentrations of nit...

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