The gene LCT codes for the enzyme lactase. In babies, lactase synthesis is necessary for digesting lactose, the sugar found in milk. Another gene, MCM6, has introns that have a regulatory role in the expression of gene LCT. Gene MCM6 codes for a protein that has no involvement in lactase synthesis. As children get older, the MCM6 introns are responsible for a decrease in lactase synthesis. This decrease in lactase synthesis is known as lactase non-persistence.
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