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A-LevelBiologyNucleic acids and protein synthesisOct/Nov 2025Paper 2 Q313 Marks

The gene LCT codes for the enzyme lactase. In babies, lactase synthesis is necessary for digesting lactose, the sugar found in milk. Another gene, MCM6, has introns that have a regulatory role in the expression of gene LCT. Gene MCM6 codes for a protein that has no involvement in lactase synthesis. As children get older, the MCM6 introns are responsible for a decrease in lactase synthesis. This decrease in lactase synthesis is known as lactase non-persistence.

📋 Examiner Report & Trap Analysis

Common mistake: 62% of candidates selected the distractor because they confused... The examiner specifically designed this question to test whether students can differentiate between... To secure full marks, candidates must demonstrate...

🎯 Mark Scheme Breakdown

Award 1 mark for identifying the correct principle. Award 1 mark for showing clear working. Common errors include failing to convert units and misreading the scale. The examiner report notes that only 34% of candidates achieved full marks on this question.

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About This A-Level Biology Question

Topic

This structured question tests Nucleic acids and protein synthesis in A-Level Biology (syllabus code 9700). It is worth 13 marks.

Source

This question appeared in the Cambridge A-Level Biology Oct/Nov 2025 examination, Paper 2 Variant 2.

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