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Cambridge Past Paper Questions

Browse 23,045questions from 25 years of O-Level & A-Level exams. Click any question to practice.

A-LevelBiologyCell structureOct/Nov 2025

Which structures will be present in a cell that causes cholera? 1 circular DNA 2 cytoplasmic DNA 3 70S ribosomes

A-LevelBiologyCell structureOct/Nov 2025

Which organelles have a partially permeable membrane? 1 Golgi apparatus 2 lysosome 3 mitochondrion 4 ribosome

A-LevelBiologyCell structureOct/Nov 2025

Mouse cells were grown in a dish containing a growth medium. Radioactively labelled amino acids were added to the growth medium. The table shows th...

A-LevelBiologyCell structureOct/Nov 2025

The electron micrograph shows a section through a cell. [Electron micrograph of a cell] What would be present in this type of cell?

A-LevelBiologyBiological moleculesOct/Nov 2025

A student carried out four tests for biological molecules. The observations are shown in the table. [Table with columns 'test' and 'observations' a...

A-LevelBiologyBiological moleculesOct/Nov 2025

The diagram shows some relationships between features of carbohydrates. [Venn diagram showing α-glucose, 1,4 bonds, highly branched and regions 1, ...

A-LevelBiologyBiological moleculesOct/Nov 2025

The diagram shows a triglyceride molecule. [Diagram of a triglyceride molecule] Which statement is correct for the structure and function of this t...

A-LevelBiologyEnzymesOct/Nov 2025

Enzyme P has been found in a tropical grass. • The enzyme catalyses the hydrolysis of the fungal polysaccharide, chitin, into amino sugars. • It al...

A-LevelBiologyBiological moleculesOct/Nov 2025

Which bonds between amino acids hold the shape of the secondary structure and also the tertiary structure of proteins?

A-LevelBiologyBiological moleculesOct/Nov 2025

Resilin is a protein found in the wings of insects. It is an elastic, fibrous protein and scientists have suggested that it may have an important r...

A-LevelBiologyBiological moleculesOct/Nov 2025

Collagen is a protein that helps to strengthen and increase the elasticity and hydration of the skin. Aging can lead to dry skin and the formation ...

A-LevelBiologyEnzymesOct/Nov 2025

What is the effect of an enzyme in an enzyme-catalysed reaction?

A-LevelBiologyEnzymesOct/Nov 2025

How is the Michaelis–Menten constant (Kₘ) used?

A-LevelBiologyEnzymesOct/Nov 2025

Some students investigated the effect of pH on the rate of starch digestion by amylase at 20 °C. • They added 2 cm³ of a 1% amylase solution and 1 ...

A-LevelBiologyEnzymesOct/Nov 2025

Which statements are correct for a non-competitive inhibitor of enzyme action? 1 Increasing the concentration of the enzyme's substrate will reduce...

A-LevelBiologyCell membranes and transportOct/Nov 2025

What can increase the fluidity of the cell surface membrane at low temperatures? 1 double bonds between carbon atoms in the fatty acid chains 2 cho...

A-LevelBiologyCell membranes and transportOct/Nov 2025

Which statements about the proteins and glycoproteins in cell surface membranes are correct? 1 They can allow cells to bond together to form tissue...

A-LevelBiologyCell membranes and transportOct/Nov 2025

In an experiment, four different-sized cubes of colourless agar were placed into a blue dye. The time taken for each cube to turn blue was recorded...

A-LevelBiologyCell membranes and transportOct/Nov 2025

The stalk of a dandelion flower is a hollow tube called a scape. Pieces of the scape are cut as shown by the dotted lines and placed in sucrose sol...

A-LevelBiologyNucleic acids and protein synthesisOct/Nov 2025

Telomeres prevent the loss of genes during DNA replication. Which row correctly shows cell types that contain telomeres?

A-LevelBiologyThe mitotic cell cycleOct/Nov 2025

Which events listed are part of mitosis? 1 interphase 2 prophase 3 cytokinesis

A-LevelBiologyThe mitotic cell cycleOct/Nov 2025

The photomicrograph shows 17 cells in different stages of the mitotic cell cycle. [Photomicrograph of cells in different mitotic stages, with cell ...

A-LevelBiologyNucleic acids and protein synthesisOct/Nov 2025

The flow diagram shows some of the stages in the replication of a lagging strand of DNA. [Flow diagram: 'The DNA double helix begins to unwind.' ->...

A-LevelBiologyNucleic acids and protein synthesisOct/Nov 2025

In a gene, the 20 common amino acids are each coded for by three bases in adjacent nucleotides. Why is there a difference between the number of ami...

A-LevelBiologyNucleic acids and protein synthesisOct/Nov 2025

How is a primary transcript modified to form mRNA?

A-LevelBiologyNucleic acids and protein synthesisOct/Nov 2025

The diagram shows protein synthesis in a prokaryote. [Diagram of protein synthesis in a prokaryote showing DNA, cell wall, X, Y, tRNA 1, tRNA 2, mR...

A-LevelBiologyTransport in plantsOct/Nov 2025

The photomicrographs show sections of two organs of a plant. [Two photomicrographs (A and B) of plant organ sections] Which letter identifies a cel...

A-LevelBiologyTransport in plantsOct/Nov 2025

Which row correctly describes the pressure in the xylem and the water potential in the root hair cells used in the transport of water in a transpir...

A-LevelBiologyTransport in plantsOct/Nov 2025

Which row correctly identifies the definitions for each of the key terms used in transpiration?

A-LevelBiologyTransport in plantsOct/Nov 2025

Which combination of features is characteristic of a phloem sieve tube element immediately after it is loaded from a source?

A-LevelBiologyTransport in mammalsOct/Nov 2025

Which blood vessel carries blood with the lowest pressure?

A-LevelBiologyTransport in mammalsOct/Nov 2025

The photomicrograph shows cells found in mammalian blood. [Photomicrograph of mammalian blood cells, with one cell labelled P] What is cell P?

A-LevelBiologyGas exchangeOct/Nov 2025

The diagram shows the Bohr shift in actively respiring cells. [Graph showing percentage saturation of haemoglobin with oxygen against partial press...

A-LevelBiologyTransport in mammalsOct/Nov 2025

The bar chart shows the mean thickness of the walls of the main chambers in a mammalian heart. [Bar chart showing mean wall thickness /mm for heart...

A-LevelBiologyGas exchangeOct/Nov 2025

The diagram shows parts of the gas exchange system in humans and the associated cells or structures. [Boxes with labels: alveolus, bronchiole, bron...

A-LevelBiologyGas exchangeOct/Nov 2025

The photomicrograph shows the wall of a bronchus as seen with a light microscope. [Photomicrograph of the wall of a bronchus with labels X, Y, Z] W...

A-LevelBiologyInfectious diseasesOct/Nov 2025

Which factors affect the global pattern of distribution of malaria? 1 the disease is mainly restricted to tropical and subtropical environments 2 t...

A-LevelBiologyImmunityOct/Nov 2025

Which molecule could be a self antigen?

A-LevelBiologyImmunityOct/Nov 2025

The diagram shows an antibody molecule with some parts labelled. [Diagram of an antibody molecule with parts P, W, V, U, R, S, T labelled] Which ro...

A-LevelBiologyCell membranes and transportOct/Nov 2025

Fig. 1.1 shows a diagram of the fluid mosaic model of the structure of the cell surface membrane.

A-LevelBiologyTransport in mammalsOct/Nov 2025

A-LevelBiologyEnzymesOct/Nov 2025

A-LevelBiologyBiological moleculesOct/Nov 2025

Fig. 4.1 is a photomicrograph of a copepod. These animals are found living in sea water and in fresh water environments.

A-LevelBiologyTransport in plantsOct/Nov 2025

Fig. 5.1 is a photomicrograph of a longitudinal section through part of the stem of a plant.

A-LevelBiologyNucleic acids and protein synthesisOct/Nov 2025

Alveolar macrophages are phagocytes found in the human gas exchange system. They produce hydrolytic enzymes, such as lysozyme, to digest pathogens ...

A-LevelBiologyCell structureOct/Nov 2025

The wall of the small intestine is highly folded to form villi. Between the villi are infoldings known as crypts of Lieberkühn. Fig. 1.1 is a diagr...

A-LevelBiologyInfectious diseasesOct/Nov 2025

Cholera is an infectious intestinal disease caused by a bacterial pathogen.

A-LevelBiologyNucleic acids and protein synthesisOct/Nov 2025

The gene LCT codes for the enzyme lactase. In babies, lactase synthesis is necessary for digesting lactose, the sugar found in milk. Another gene, ...

A-LevelBiologyCell membranes and transportOct/Nov 2025

Bacteria can be classified according to the type of cell wall they have. Gram-negative bacteria have a cell wall with an outer layer known as the o...

A-LevelBiologyTransport in plantsOct/Nov 2025

A plant that is described as a mesophyte has evolved to grow in conditions that do not normally experience water stress (low availability of water)...

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