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A-LevelBiologyNucleic acids and protein synthesis9700/12 · Oct/Nov 2025 · Q241 Mark

The flow diagram shows some of the stages in the replication of a lagging strand of DNA. [Flow diagram: 'The DNA double helix begins to unwind.' -> 'The single strands of DNA are exposed.' -> 'New complementary DNA fragments are synthesised in the 5' to 3' direction.' -> 'The fragments of newly formed DNA are linked together.'] Which stage of DNA replication uses the enzyme DNA ligase?

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AThe DNA double helix begins to unwind.
BThe single strands of DNA are exposed.
CNew complementary DNA fragments are synthesised in the 5' to 3' direction.
DThe fragments of newly formed DNA are linked together.

✓ Correct answer

D: The fragments of newly formed DNA are linked together.

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About this question

Topic
Nucleic acids and protein synthesis, A-Level Biology (syllabus 9700). Multiple choice, 1 mark.
Source
A-Level Biology, Oct/Nov 2025 Paper 1 Variant 2, question 24.

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