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Cambridge Past Paper Questions

Browse 23,045questions from 25 years of O-Level & A-Level exams. Click any question to practice.

A-LevelBiologyGas exchangeFeb/Mar 2023

What is an effect of an increased concentration of carbon dioxide in the blood?

A-LevelBiologyGas exchangeFeb/Mar 2023

Two of the requirements of an efficient gas exchange system are a large surface area and a short diffusion distance. Which row correctly describes ...

A-LevelBiologyInfectious diseasesFeb/Mar 2023

What defines infectious diseases?

A-LevelBiologyInfectious diseasesFeb/Mar 2023

A hurricane destroys a large town on an island. People move away from the town and set up tents, where sanitation is poor. Which disease is most li...

A-LevelBiologyInfectious diseasesFeb/Mar 2023

Which statement correctly explains why viruses are unaffected by penicillin?

A-LevelBiologyImmunityFeb/Mar 2023

Which processes characterise the mode of action of phagocytes? 1 antibody production 2 receptor binding 3 endocytosis 4 exocytosis 5 hydrolysis

A-LevelBiologyCell structureFeb/Mar 2023

Table 1.1 lists cell structures that can be found in eukaryotic cells or prokaryotic cells. Some of these cell structures can be found in both type...

A-LevelBiologyBiological moleculesFeb/Mar 2023

Cysteine is an amino acid containing sulfur. Fig. 2.1 shows the structure of the molecule formed by joining two cysteine molecules together. SH H-O...

A-LevelBiologyTransport in plantsFeb/Mar 2023

Fig. 3.1 is a diagram of an area of phloem tissue from a transverse section through the stem of a squash plant, Cucurbita pepo. X Y companion cell ...

A-LevelBiologyImmunityFeb/Mar 2023

Tuberculosis (TB), influenza and polio are examples of infectious diseases.

A-LevelBiologyGas exchangeFeb/Mar 2023

Pneumonia is a severe lung disease that can interfere with gas exchange. A person with pneumonia can be connected to an ECMO machine. This machine ...

A-LevelBiologyEnzymesFeb/Mar 2023

Collagen is the most common structural protein in vertebrates. Collagen provides the skin with flexibility and strength.

A-LevelBiologyCell membranes and transportFeb/Mar 2023

(a) You will investigate the effect of different temperatures on the permeability of the cell surface membrane of beetroot cells. Beetroot is a ve...

A-LevelBiologyTransport in plantsFeb/Mar 2023

P1 is a slide of a stained transverse section through a plant root.

A-LevelBiologyHomeostasisFeb/Mar 2023

Fig. 1.1 is a drawing of a longitudinal section (LS) of a human kidney. [Figure 1.1]

A-LevelBiologyGenetic technologyFeb/Mar 2023

Interferon-alpha (IFN-α) can be produced as a recombinant human protein to treat some types of cancer. The gene IFNA2 codes for IFN-α. One method o...

A-LevelBiologyInherited changeFeb/Mar 2023

Salmon can be genetically modified (GM) to produce increased quantities of growth hormone, which is a protein. GM salmon modified in this way have ...

A-LevelBiologyGenetic technologyFeb/Mar 2023

Array comparative genome hybridisation (aCGH) is a technique involving the use of a microarray to analyse a genome or sections of a genome.

A-LevelBiologyThe mitotic cell cycleFeb/Mar 2023

Meiosis is described as a reduction division because the number of chromosomes in the daughter cells is reduced by half.

A-LevelBiologyEnergy and respirationFeb/Mar 2023

(a) Fig. 6.1 is a diagram of a section through a mitochondrion. [Figure 6.1]

A-LevelBiologyControl and coordinationFeb/Mar 2023

(a) Fig. 7.1 is a diagram representing a synapse between a chemoreceptor cell from a human taste bud and a dendrite of a sensory neurone. [Figure 7.1]

A-LevelBiologyPhotosynthesisFeb/Mar 2023

A-LevelBiologyControl and coordinationFeb/Mar 2023

(a) Fig. 9.1 is a diagram of a relaxed sarcomere in striated muscle. [Figure 9.1]

A-LevelBiologyBiodiversity and conservationFeb/Mar 2023

A-LevelBiologyBiological moleculesFeb/Mar 2023

Potatoes are underground organs made by the potato plant, Solanum tuberosum. Fig. 1.1 shows a potato plant. [Figure 1.1] Potatoes contain high quan...

A-LevelBiologyGenetic technologyFeb/Mar 2023

Rice, Oryza sativa, is an important food crop. Rice plants are wind pollinated. Pollen containing the male gamete is transferred by the wind to fem...

A-LevelBiologyCell structureFeb/Mar 2024

A student used a light microscope to observe a blood smear on a microscope slide. An eyepiece graticule was used to measure the diameter of a white...

A-LevelBiologyCell structureFeb/Mar 2024

Which statement explains why it is necessary to use an electron microscope to see the cristae of a mitochondrion?

A-LevelBiologyCell structureFeb/Mar 2024

Some stains can be used to identify cell structures in living cells. A dilute solution of one stain causes the whole cell to appear blue. The blue ...

A-LevelBiologyCell structureFeb/Mar 2024

When mucus is secreted from a goblet cell, these events take place. 1 addition of carbohydrate to protein 2 fusion of a vesicle with the cell surfa...

A-LevelBiologyCell structureFeb/Mar 2024

The diagram shows four biological features. 4 RNA, 1 DNA, 3 70S ribosomes, 2 capsid. Which biological features are present in typical prokaryotes? ...

A-LevelBiologyCell structureFeb/Mar 2024

Which row shows features that occur in dicotyledonous plant cells and also in typical bacterial cells? key ✓ = found in dicotyledonous plant cells ...

A-LevelBiologyBiological moleculesFeb/Mar 2024

Which flow chart outlining the test for non-reducing sugars is correct? [Figure 7.1]

A-LevelBiologyBiological moleculesFeb/Mar 2024

Which diagrams show the release of a water molecule during the formation of a glycosidic bond? [Figure 8.1]

A-LevelBiologyBiological moleculesFeb/Mar 2024

Which molecules have a structural formula that contains C=O bonds? 1 amino acids 2 fatty acids 3 glycerol 4 protein

A-LevelBiologyBiological moleculesFeb/Mar 2024

Which statement about triglycerides is correct?

A-LevelBiologyEnzymesFeb/Mar 2024

Many flowers produce a sweet solution called nectar. Bees provided with nectar use enzyme Q to change the nectar into honey. After testing a sample...

A-LevelBiologyBiological moleculesFeb/Mar 2024

The diagram shows the structure of part of a peptidoglycan molecule. [Figure 12.1]

A-LevelBiologyEnzymesFeb/Mar 2024

A scientist investigated the progress of two enzyme-catalysed reactions in separate test-tubes, X and Y. Both reactions result in colour changes th...

A-LevelBiologyEnzymesFeb/Mar 2024

A student investigated the hydrolysis of lipid in high-fat milk, using the enzyme lipase. • 1 cm³ of enzyme solution was added to 10 cm³ of high-fa...

A-LevelBiologyCell membranes and transportFeb/Mar 2024

Where in the cell surface membrane are the carbohydrate chains of glycoproteins and glycolipids mainly located?

A-LevelBiologyCell membranes and transportFeb/Mar 2024

Sodium ions can enter cells across the cell surface membrane. Which methods could be used by sodium ions to cross a cell surface membrane and enter...

A-LevelBiologyCell membranes and transportFeb/Mar 2024

The diagram shows how an artificial partially permeable membrane was used to separate a 5% sodium chloride solution and a 10% sodium chloride solut...

A-LevelBiologyCell membranes and transportFeb/Mar 2024

Agar cubes can be used to demonstrate the effect on diffusion of changing the surface area to volume ratio. Three different agar cubes made using a...

A-LevelBiologyNucleic acids and protein synthesisFeb/Mar 2024

During sperm formation in mammals, part of the structure of each chromosome is replaced with proteins called protamines. This replacement allows th...

A-LevelBiologyThe mitotic cell cycleFeb/Mar 2024

The diagram shows the mitotic cell cycle. During which phase do chromosomes condense and become visible? [Figure 21.1]

A-LevelBiologyThe mitotic cell cycleFeb/Mar 2024

Which statements correctly describe features of stem cells that are essential for their role in cell replacement and tissue repair? 1 After mitosis...

A-LevelBiologyNucleic acids and protein synthesisFeb/Mar 2024

Which statements are correct for all nucleotides? 1 The nitrogen-containing base is always attached to carbon atom 1 of the pentose. 2 The phosphat...

A-LevelBiologyNucleic acids and protein synthesisFeb/Mar 2024

How many phosphodiester bonds are present in a circular DNA molecule of 2700 base pairs?

A-LevelBiologyNucleic acids and protein synthesisFeb/Mar 2024

Which statements about complementary base pairing are correct? 1 Purines and pyrimidines are different sizes. 2 Complementary base pairing occurs d...

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