During aerobic respiration, cells respire substrates such as glucose to produce ATP. Some events that occur during aerobic respiration are: • The respiratory substrate breaks down into smaller and smaller molecules. These series of reactions are described as catabolism. • Coenzymes take part in various reactions. In some reactions, coenzymes are reduced or oxidised. • Carbon dioxide is released.
- (a)Aerobic respiration occurs in four successive stages: glycolysis (G), link reaction (LR), Krebs cycle (KC) and oxidative phosphorylation (OP). Complete Table 3.1 to show which events occur in each stage of aerobic respiration. Use a tick (✔) to show that the event does occur or a cross (X) to show that the event does not occur.[4]
- (b)(i)A new hand-held technological device shows the main type of respiratory substrate being used in the cells of a person. The device consists of a carbon dioxide sensor and air-flow meter. The person inhales through the device for a fixed time and then exhales into it. The device calculates the respiratory quotient (RQ) value to show whether the cells are mainly respiring carbohydrates or lipids. Explain how the device calculates the RQ value and how this shows whether the cells are mainly respiring carbohydrates or lipids.[4]
- (b)(ii)State the difference in the relative energy values of carbohydrates and lipids as respiratory substrates, and explain the reasons for the difference.[3]
Mark scheme
Marking points from the official mark scheme (Oct/Nov 2024). The mark or mark type is shown in brackets.
- [4] (Table with ticks and crosses)
- catabolism: G(✔), LR(✔), KC(✔), OP(X);
- coenzyme is reduced or oxidised: G(✔), LR(✔), KC(✔), OP(✔);
- a coenzyme forms a covalent bond with a respiratory intermediate: G(X), LR(X), KC(X), OP(X);
- carbon dioxide is released: G(X), LR(✔), KC(✔), OP(X);
- [4] any four from:
- 1 (RQ =) ratio of carbon dioxide (exhaled) to oxygen (inhaled) ;
- 2 air flow meter measures oxygen inhaled ;
- 3 carbon dioxide sensor measures concentration of CO2 exhaled ;
- 4 carbohydrate RQ = 1 ;
- 5 lipid RQ = 0.7 ;
- [3] any three from:
- 1 lipid has higher energy (value) OR carbohydrate 15–17 kJ g⁻¹ and lipid 37–40 kJ g⁻¹ ;
- 2 more, hydrogen (atoms) / C-H bonds, in lipid ;
- 3 more reduced, NAD / FAD ;
- 4 greater proton gradient / more protons in intermembrane space / more protons pass through ATP synth(et)ase ;
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