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Cambridge Past Paper Questions

Browse 23,045questions from 25 years of O-Level & A-Level exams. Click any question to practice.

A-LevelBiologyImmunityFeb/Mar 2016

An enzyme hydrolyses the two heavy polypeptide chains of an antibody molecule. The hydrolysis occurs at the hinge region and breaks the antibody in...

A-LevelBiologyCell structureFeb/Mar 2017

The diagram shows the ultrastructure of a typical animal cell. Which structure synthesises and transports lipids? [Figure 1.1]

A-LevelBiologyCell structureFeb/Mar 2017

A light microscope is used to observe two structures that are 200 nm apart. How far apart are the structures when the magnification is changed from...

A-LevelBiologyCell structureFeb/Mar 2017

The diagram shows a stage micrometer scale viewed through an eyepiece containing a graticule. The small divisions of the stage micrometer scale are...

A-LevelBiologyCell structureFeb/Mar 2017

Some features of cells are listed. 1 cytoplasm 2 cell surface membrane 3 ribosomes Which features are found in both animal and prokaryotic cells?

A-LevelBiologyCell structureFeb/Mar 2017

Which size of ribosomes is found in chloroplasts?

A-LevelBiologyEnergy and respirationFeb/Mar 2017

In which of these organelles is ATP synthesised? [Figure 6.1]

A-LevelBiologyBiological moleculesFeb/Mar 2017

A sample of milk is tested with Benedict's solution. After boiling, a yellow colour is observed. Which conclusion is correct?

A-LevelBiologyBiological moleculesFeb/Mar 2017

The table shows some information about carbohydrate polymers. Which row describes amylose? [Table 8.1]

A-LevelBiologyBiological moleculesFeb/Mar 2017

Which row about α-glucose and β-glucose molecules is correct? [Table 9.1]

A-LevelBiologyBiological moleculesFeb/Mar 2017

Some of the molecules found in animal tissues are grouped into three lists. 1 glucose, cholesterol, triglycerides, water 2 glycogen, antibodies, ad...

A-LevelBiologyBiological moleculesFeb/Mar 2017

Haemoglobin consists of two α chains and two β chains. Approximately 5% of all humans have one amino acid in the β chain that has been changed, aff...

A-LevelBiologyBiological moleculesFeb/Mar 2017

Which row gives the correct description of both a collagen molecule and a collagen fibre? [Table 12.1]

A-LevelBiologyBiological moleculesFeb/Mar 2017

The diagrams show the structures of two amino acids, each of which has two amine (–NH2) groups. A peptide bond is formed between the two amino acid...

A-LevelBiologyEnzymesFeb/Mar 2017

An enzyme was added to a small excess of its substrate. All variables were kept constant. A student was asked to sketch a graph to show how the con...

A-LevelBiologyEnzymesFeb/Mar 2017

The table contains results recorded by a student from an investigation into the effect of temperature on an enzyme-catalysed reaction. All other va...

A-LevelBiologyCell membranes and transportFeb/Mar 2017

What is the correct range of measurements for the width of the cell surface membrane?

A-LevelBiologyCell membranes and transportFeb/Mar 2017

The cells in the roots of beetroot plants contain a red pigment. When pieces of root tissue are soaked in cold water, some of the red pigment leaks...

A-LevelBiologyCell membranes and transportFeb/Mar 2017

The cell surface membrane structure is described as a 'fluid mosaic'. Which statement describes the 'mosaic' part of the cell surface membrane?

A-LevelBiologyCell membranes and transportFeb/Mar 2017

The diagram shows two pathways, X and Y, through which molecules can diffuse across a cell surface membrane. Which row correctly shows possible pat...

A-LevelBiologyImmunityFeb/Mar 2017

Some stem cells divide and give rise to phagocytes. Where in the human body do these stem cells divide? 1 blood 2 bone marrow 3 lymph nodes

A-LevelBiologyThe mitotic cell cycleFeb/Mar 2017

What is the correct sequence of stages in the mitotic cell cycle?

A-LevelBiologyThe mitotic cell cycleFeb/Mar 2017

The enzyme telomerase repairs telomeres. It stops the telomeres from getting shorter each time a chromosome is replicated. Telomerase is not normal...

A-LevelBiologyThe mitotic cell cycleFeb/Mar 2017

The statements describe events during the mitotic cell cycle. 1 Chromosomes migrate to opposite poles of the spindle. 2 Chromosomes arrange themsel...

A-LevelBiologyNucleic acids and protein synthesisFeb/Mar 2017

Which statement about nitrogenous bases is correct?

A-LevelBiologyNucleic acids and protein synthesisFeb/Mar 2017

Rifampicin is an antibiotic used to treat tuberculosis. It works by inhibiting RNA polymerase in bacteria. Which of these processes will be directl...

A-LevelBiologyNucleic acids and protein synthesisFeb/Mar 2017

Meselson and Stahl investigated DNA in bacteria. They grew bacteria in a medium with only heavy nitrogen, 15N, until all of the bacterial DNA conta...

A-LevelBiologyNucleic acids and protein synthesisFeb/Mar 2017

The diagram shows the stages in the production of part of a polypeptide. Which feature of the triplet code is illustrated by the information given?...

A-LevelBiologyTransport in plantsFeb/Mar 2017

Which combination of features is characteristic of a phloem sieve tube element as it unloads into a sink? [Table 28.1]

A-LevelBiologyTransport in plantsFeb/Mar 2017

Which statements correctly describe transport pathways in dicotyledonous plants? 1 In the symplast pathway, water may move through intercellular sp...

A-LevelBiologyTransport in plantsFeb/Mar 2017

The diagrams show transverse sections of parts of a plant. Which labelled structures transport mineral ions? [Figure 30.1]

A-LevelBiologyTransport in plantsFeb/Mar 2017

Which feature of transport in plants is correct for both xylem and phloem?

A-LevelBiologyTransport in plantsFeb/Mar 2017

What is the main function of a companion cell in phloem tissue?

A-LevelBiologyTransport in mammalsFeb/Mar 2017

The contraction of the heart is coordinated through electrical impulses passing through the cardiac muscle. What is the correct order of part of th...

A-LevelBiologyTransport in mammalsFeb/Mar 2017

As blood flows from an artery to a vein, the thickness of the walls of the vessels changes. Which bar chart shows these changes correctly? [Figure ...

A-LevelBiologyGas exchangeFeb/Mar 2017

The graph shows the oxygen dissociation curves of haemoglobin from two species of mammal, S and T. Which statements could explain the difference in...

A-LevelBiologyGas exchangeFeb/Mar 2017

Which tissues may be found in bronchioles?

A-LevelBiologyGas exchangeFeb/Mar 2017

Which of these statements could describe the effect of carbon monoxide in cigarette smoke? 1 It binds irreversibly to haemoglobin. 2 It causes mucu...

A-LevelBiologyInfectious diseasesFeb/Mar 2017

The global mortality figures for some diseases in 2002 are shown in the table. How many millions of people died from viral diseases listed in the t...

A-LevelBiologyImmunityFeb/Mar 2017

Which of the statements could describe both B-lymphocytes and T-lymphocytes? 1 They contain specific protein receptors in their cell surface membra...

A-LevelBiologyImmunityFeb/Mar 2017

Two people, G and H, were each given an injection to protect them against a particular pathogen. One person was injected with antibodies. The other...

A-LevelBiologyThe mitotic cell cycleFeb/Mar 2017

A diagram of a chromosome from a dividing cell is shown in Fig. 1.1. [Figure 1.1]

A-LevelBiologyCell structureFeb/Mar 2017

The infectious disease cholera is caused by a bacterium. (a) Fig. 2.1 shows a transmission electron micrograph of this bacterium. ×30 000 [Figure 2.1]

A-LevelBiologyEnzymesFeb/Mar 2017

Catalase is an enzyme that catalyses the breakdown of hydrogen peroxide, a toxic waste product of metabolism. 2H2O2 catalase 2H2O + O2 Fig. 3.1 sho...

A-LevelBiologyTransport in mammalsFeb/Mar 2017

The transport systems of plants and mammals both function to transport substances to and from cells. (a) Table 4.1 contains descriptions concerning...

A-LevelBiologyGas exchangeFeb/Mar 2017

(a) Smooth muscle and cartilage are two of the tissues found in the walls of structures of the gas exchange system of mammals. Complete Fig. 5.1 to...

A-LevelBiologyCell membranes and transportFeb/Mar 2017

(a) A student investigated the effect of changing the surface area to volume ratio on diffusion. • Two different-sized blocks of agar, X and Y, wer...

A-LevelBiologyEnzymesFeb/Mar 2017

Enzyme E hydrolyses (breaks down) starch to reducing sugar. You are required to investigate the effect of temperature (independent variable) on the...

A-LevelBiologyTransport in plantsFeb/Mar 2017

P1 is a slide of a stained transverse section through a plant root. You are not expected to be familiar with this specimen. Use a sharp pencil for ...

A-LevelBiologyHomeostasisFeb/Mar 2017

Section A Answer all the questions. (a) Fig. 1.1 shows diagrams of nephrons from the kidneys of three different mammals, P, Q and R. These are all ...

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