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Cambridge & Pearson Edexcel Past Paper Questions

Browse 35,704 questions from Cambridge O-Level & A-Level and Pearson Edexcel IGCSE & IAL exams. Click any question to practice.

A-LevelBiologyNucleic acids and protein synthesisMay/June 2024

Which statements about peptide bond formation are correct? 1 The bond formation occurs between a carbon of one amino acid and a nitrogen of the nex...

A-LevelBiologyEnzymesMay/June 2024

The diagram shows naturally occurring D-glucose and a form of glucose that can be synthesised in the laboratory, known as L-glucose. [Diagram of D-...

A-LevelBiologyBiological moleculesMay/June 2024

Tests for biological molecules were carried out on three solutions. Each solution contained only one type of biological molecule. The observations ...

A-LevelBiologyEnzymesMay/June 2024

Which row describes the expected effect on Vmax and Km when a competitive reversible inhibitor is added to an enzyme-catalysed reaction? [Table wit...

A-LevelBiologyEnzymesMay/June 2024

The graph shows the effect of substrate concentration on the rates of reaction of three enzymes, X, Y, and Z. [Graph showing rate of reaction vs su...

A-LevelBiologyBiological moleculesMay/June 2024

Which row correctly identifies the weak and strong bonds in the tertiary and quaternary structure of a typical protein? [Table with columns 'disulf...

A-LevelBiologyBiological moleculesMay/June 2024

Which row correctly describes haemoglobin? [Table with four columns describing aspects of haemoglobin]

A-LevelBiologyCell membranes and transportMay/June 2024

Which process always takes place without the involvement of energy from ATP?

A-LevelBiologyCell membranes and transportMay/June 2024

The diagram shows the entry of molecule X into a cell. [Diagram of molecule X entering a cell] Which row shows a property of molecule X and the eff...

A-LevelBiologyCell membranes and transportMay/June 2024

The electron micrograph shows some human blood cells. [Electron micrograph of human blood cells with one cell labelled X] Which row correctly shows...

A-LevelBiologyCell membranes and transportMay/June 2024

A red indicator solution was mixed with agar and the resulting solid was cut into small cylindrical blocks. The blocks were placed in an acid which...

A-LevelBiologyThe mitotic cell cycleMay/June 2024

Which metabolic processes will be very active in a cell that has just completed cytokinesis? 1 ATP formation 2 DNA replication 3 protein synthesis

A-LevelBiologyThe mitotic cell cycleMay/June 2024

The diagram shows a typical mitotic cell cycle and the point in the cell cycle that has been reached by each of four cells, V, W, X and Y. [Diagram...

A-LevelBiologyThe mitotic cell cycleMay/June 2024

The graph shows the mean length of the spindle fibres during mitosis. [Graph showing mean length of spindle fibres over time, with regions A, B, C,...

A-LevelBiologyNucleic acids and protein synthesisMay/June 2024

The mRNA codons ACU, ACC, ACA and ACG all code for the same amino acid, threonine. Which anticodons could specify an amino acid other than threonin...

A-LevelBiologyNucleic acids and protein synthesisMay/June 2024

Which bond formation does DNA polymerase catalyse?

A-LevelBiologyNucleic acids and protein synthesisMay/June 2024

In eukaryotes, the RNA molecules formed during transcription are modified by the removal of non-coding sequences. This is followed by the joining t...

A-LevelBiologyTransport in plantsMay/June 2024

Which row correctly identifies sinks for sucrose transported by mass flow in plants? [Table with columns 'root storage organ', 'growing leaf bud', ...

A-LevelBiologyTransport in plantsMay/June 2024

The diagram shows a transverse section through a transport tissue in a plant. [Diagram of transverse section through a transport tissue with cells ...

A-LevelBiologyTransport in plantsMay/June 2024

Which statement correctly describes the movement of solutes in the symplast pathway?

A-LevelBiologyTransport in plantsMay/June 2024

Which statement helps to explain why water molecules are forced to move through xylem vessel elements as a consequence of transpiration?

A-LevelBiologyTransport in mammalsMay/June 2024

The diagram shows the internal structure of the mammalian heart. [Diagram of mammalian heart with locations A, B, C, D labelled] Which letter ident...

A-LevelBiologyTransport in mammalsMay/June 2024

The diagram shows pressure changes in the left side of the heart during the cardiac cycle. [Graph showing pressure changes in the left side of the ...

A-LevelBiologyTransport in mammalsMay/June 2024

Which components of blood are present in tissue fluid? [Table with columns 'phagocytes', 'some proteins', 'sodium ions'] key: ✓ = present x = not p...

A-LevelBiologyGas exchangeMay/June 2024

In the lungs, movement of dissolved carbon dioxide out of the capillaries occurs in one of two ways: • by diffusion through the endothelial cells o...

A-LevelBiologyGas exchangeMay/June 2024

What maintains the steep concentration gradients needed for successful gas exchange in the lungs? 1 Air flow in the alveoli is in the opposite dire...

A-LevelBiologyGas exchangeMay/June 2024

Where is cartilage tissue always found in the human gas exchange system?

A-LevelBiologyGas exchangeMay/June 2024

Scientists compared the density of goblet cells in the lungs and the density of mucus in the lungs of three groups of people: • people who do not s...

A-LevelBiologyInfectious diseasesMay/June 2024

Which disease does *Mycobacterium bovis* cause?

A-LevelBiologyInfectious diseasesMay/June 2024

An antibiotic inhibits the formation of cross-links between the molecules that form cell walls in bacteria. Which statements explain why bacteria a...

A-LevelBiologySelection and evolutionMay/June 2024

Scientists investigated the effect of increasing concentrations of an antibiotic on the development of antibiotic resistance in bacteria. The scien...

A-LevelBiologyImmunityMay/June 2024

What is the correct sequence of events in a primary immune response?

A-LevelBiologyImmunityMay/June 2024

Which statement about the properties of the antigen-binding sites in different antibody molecules is correct?

A-LevelBiologyGenetic technologyMay/June 2024

The diagram shows a stage in monoclonal antibody production. [Diagram showing 'X' + 'cancer cells' -> 'hybridoma cells'] What is represented by X?

A-LevelBiologyCell membranes and transportMay/June 2024

Fig. 1.1 is a diagram showing part of a cell surface membrane of an animal cell. [Figure 1.1] Fig. 1.2 is a drawing of a transmission electron micr...

A-LevelBiologyTransport in mammalsMay/June 2024

Fig. 2.1 is a diagram of the circulation in a mammal. [Figure 2.1] Fig. 2.2 is a transmission electron micrograph of a cross-section of an arteriol...

A-LevelBiologyInfectious diseasesMay/June 2024

A class of students was studying the features of some human pathogens. One of the students constructed a flow chart to identify four different huma...

A-LevelBiologyGas exchangeMay/June 2024

Fig. 4.1 is a scanning electron micrograph showing the tissue that lines the bronchi in the gas exchange system. Fig. 4.2 is a transmission electro...

A-LevelBiologyTransport in plantsMay/June 2024

The pressure of water vapour inside and outside leaves can be measured. The difference between these pressures is known as the leaf vapour pressure...

A-LevelBiologyImmunityMay/June 2024

Antibodies are produced by plasma cells. Fig. 6.1 shows antigens bound to antigen-binding sites of an antibody molecule. [Figure 6.1] It is estimat...

A-LevelBiologyGas exchangeMay/June 2024

Smooth muscle is a tissue composed of smooth muscle cells. The cells contain cytoplasm packed with proteins that are involved in contraction and re...

A-LevelBiologyCell structureMay/June 2024

Alveolar macrophages are cells of the immune system that remain in the alveolar region of the gas exchange system. The macrophages protect against ...

A-LevelBiologyEnzymesMay/June 2024

Lysozyme is an antibacterial enzyme that was discovered in 1921 by Alexander Fleming, the scientist who discovered penicillin. Lysozyme catalyses t...

A-LevelBiologyBiological moleculesMay/June 2024

In the mesophyll tissue of leaves, products of photosynthesis can be used to synthesise organic compounds, such as the polysaccharide cellulose and...

A-LevelBiologyThe mitotic cell cycleMay/June 2024

During interphase of the cell cycle, individual chromosomes cannot be seen within the nucleus. The genetic material is termed chromatin during this...

A-LevelBiologyImmunityMay/June 2024

Some people who are infected with HIV have HIV/AIDS.

A-LevelBiologyCell structureMay/June 2024

The Zika virus is a pathogen that can infect human cells.

A-LevelBiologyBiological moleculesMay/June 2024

Collagen is a fibrous protein that is found in many tissues in animals.

A-LevelBiologyTransport in mammalsMay/June 2024

Arteries, capillaries and veins are three types of blood vessel.

A-LevelBiologyTransport in plantsMay/June 2024

Lignin and suberin are polymers that are present in plant tissues.

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