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Cambridge Past Paper Questions

Browse 23,045questions from 25 years of O-Level & A-Level exams. Click any question to practice.

A-LevelBiologyCell membranes and transportFeb/Mar 2025

Which molecule forms a bilayer in the cell surface membrane of a bacterial cell?

A-LevelBiologyThe mitotic cell cycleFeb/Mar 2025

A nucleus in a body cell of a species of fruit fly has 8 chromosomes. How many strands of DNA are present in the nucleus at the end of interphase?

A-LevelBiologyThe mitotic cell cycleFeb/Mar 2025

The photomicrograph shows plant cells in different stages of the mitotic cell cycle. Four of the cells are labelled with a number to identify them....

A-LevelBiologyThe mitotic cell cycleFeb/Mar 2025

Which percentage of the chromosomal DNA present in a cell during G₁ is present in the same cell later in the same mitotic cell cycle during prophas...

A-LevelBiologyThe mitotic cell cycleFeb/Mar 2025

The statements are about two genes and their protein products that can have a role in tumour formation. • The protein coded for by the PTEN gene pr...

A-LevelBiologyThe mitotic cell cycleFeb/Mar 2025

Telomerase is an enzyme that prevents the shortening of telomeres. It is not present in most normal cells, but is active in an estimated 85% to 95%...

A-LevelBiologyNucleic acids and protein synthesisFeb/Mar 2025

Which diagram correctly represents one of the base pairs of DNA?

A-LevelBiologyNucleic acids and protein synthesisFeb/Mar 2025

The diagram represents the process of transcription of a gene in the nucleus of an animal cell. [Figure 25.1] Which row correctly identifies P, Q a...

A-LevelBiologyTransport in plantsFeb/Mar 2025

Which row correctly describes the role of growing leaves as sources or sinks for amino acids and sucrose?

A-LevelBiologyCell structureFeb/Mar 2025

Which row correctly matches each description to cilia or root hairs?

A-LevelBiologyTransport in plantsFeb/Mar 2025

Which changes occur as amino acids are moved into phloem sieve tubes at a source?

A-LevelBiologyGas exchangeFeb/Mar 2025

The graph shows the dissociation curves for haemoglobin at two different partial pressures of carbon dioxide. Which labelled point on the oxygen di...

A-LevelBiologyGas exchangeFeb/Mar 2025

Which statements about the transport of carbon dioxide in the blood are correct? 1 Carbonic anhydrase catalyses the reaction of carbon dioxide and ...

A-LevelBiologyTransport in mammalsFeb/Mar 2025

What happens as a result of the blood pressure in the left ventricle becoming higher than the blood pressure in the left atrium?

A-LevelBiologyGas exchangeFeb/Mar 2025

The scanning electron micrograph shows the inner surface of a human trachea. [Figure 32.1] What is the identity of the part of the electron microgr...

A-LevelBiologyGas exchangeFeb/Mar 2025

Which rows correctly summarise the typical distribution of cartilage and smooth muscle within different parts of the gas exchange system of humans?

A-LevelBiologyCell membranes and transportFeb/Mar 2025

A molecule of oxygen diffuses from the air in an alveolus to haemoglobin in a red blood cell. Assuming that the molecule crosses cellular layers by...

A-LevelBiologyInfectious diseasesFeb/Mar 2025

Which row shows the type of pathogen that causes cholera and its mode of transmission?

A-LevelBiologyInfectious diseasesFeb/Mar 2025

Which statement about tuberculosis (TB) is not correct?

A-LevelBiologyInfectious diseasesFeb/Mar 2025

More cases of malaria are being reported in Europe. Other diseases, formerly confined to tropical countries and transmitted in the same way as mala...

A-LevelBiologyBiological moleculesFeb/Mar 2025

The diagrams show three different bonds. [Figure 38.1] Which bonds are found in an antibody molecule?

A-LevelBiologyImmunityFeb/Mar 2025

Specific monoclonal antibodies can be used to treat some forms of cancer. One example is trastuzumab, which can be used in the treatment of tumours...

A-LevelBiologyImmunityFeb/Mar 2025

The HIV virus causes illness by infecting and destroying T-helper cells. This leads to AIDS and an inability to produce an effective immune respons...

A-LevelBiologyTransport in plantsFeb/Mar 2025

Smilax china is a herbaceous plant. Fig. 1.1 shows part of a transverse section of a root of S. china with root hair cells visible. [Figure 1.1]

A-LevelBiologyBiological moleculesFeb/Mar 2025

A-LevelBiologyTransport in mammalsFeb/Mar 2025

Fig. 3.1 and Fig. 3.2 are diagrams of transverse sections of the human heart during different stages of the cardiac cycle. The sections pass throug...

A-LevelBiologyImmunityFeb/Mar 2025

A-LevelBiologyNucleic acids and protein synthesisFeb/Mar 2025

A-LevelBiologyThe mitotic cell cycleFeb/Mar 2025

A-LevelBiologyEnergy and respirationFeb/Mar 2025

Different types of respiratory substrate can have different energy values and therefore release different quantities of energy when they are respir...

A-LevelBiologySelection and evolutionFeb/Mar 2025

The orca, Orcinus orca, has the largest distribution of all aquatic mammals and is found in nearly all seas and oceans. Orca are social mammals tha...

A-LevelBiologyGenetic technologyFeb/Mar 2025

Gentamicin is an antibiotic used to treat severe bacterial infections in children. (a) Some children have a genetic mutation in the gene MT-RNR1. I...

A-LevelBiologyInherited changeFeb/Mar 2025

The HFE gene codes for the HFE protein, which has a role in the regulation of iron absorption by the body. Iron is an essential mineral that can be...

A-LevelBiologyThe mitotic cell cycleFeb/Mar 2025

[Figure 5.1] shows a photomicrograph of a single plant cell in a stage of meiosis. Describe the stage of meiosis shown in Fig. 5.1.

A-LevelBiologyHomeostasisFeb/Mar 2025

[Figure 6.1] outlines part of the control mechanism that regulates blood glucose concentration.

A-LevelBiologyBiodiversity and conservationFeb/Mar 2025

The Sumatran tiger, Panthera tigris sumatrae, is classified as critically endangered on the International Union for Conservation of Nature (IUCN) R...

A-LevelBiologyEnergy and respirationFeb/Mar 2025

(a) In the link reaction, a two-carbon acetyl group is produced from pyruvate. The acetyl group is transferred to coenzyme A to form acetyl coenzym...

A-LevelBiologyPhotosynthesisFeb/Mar 2025

The chloroplasts of leaves of tobacco plants, Nicotiana sp., contain chlorophyll a and chlorophyll b. (a) Describe the role of chlorophyll b in pho...

A-LevelBiologyControl and coordinationFeb/Mar 2025

(a) Fig. 10.1 shows chemoreceptor cells in a taste bud. Two of the chemoreceptor cells have formed synapses with sensory neurone dendrites. [Figure...

A-LevelBiologyBiodiversity and conservationFeb/Mar 2025

Sand dunes are important ecosystems that are found in many regions of the world. Sand dune ecosystems can be damaged by natural events, such as ext...

A-LevelBiologyBiodiversity and conservationFeb/Mar 2025

Nagarahole National Park in southern India is a forest ecosystem that is important for the conservation of large mammals such as the Asian elephant...

A-LevelBiologyImmunityFeb/Mar 2025

Type 1 diabetes is a disease that occurs when the pancreas stops producing insulin. Type 1 diabetes occurs most commonly in children and is often t...

A-LevelBiologyGas exchangeMay/June 2010

The diagram shows a section through a type of epithelium. [Figure 1.1] Where is this type of epithelium found in the respiratory system?

A-LevelBiologyInfectious diseasesMay/June 2010

Which statement is an example of epidemiological evidence linking smoking to lung cancer?

A-LevelBiologyBiological moleculesMay/June 2010

Which feature of haemoglobin makes it a globular protein?

A-LevelBiologyCell membranes and transportMay/June 2010

Which processes allow movement into and out of a cell? 1 active transport 2 diffusion 3 facilitated diffusion 4 osmosis

A-LevelBiologyCell membranes and transportMay/June 2010

Some plant and animal cells were placed in different solutions and the results are shown. [Figure 5.1] Which cells were placed in which solution?

A-LevelBiologyTransport in plantsMay/June 2010

The diagrams represent the cross section of the stem, root and leaf of a non-woody dicotyledonous plant. In each section the distribution of the ti...

A-LevelBiologyTransport in plantsMay/June 2010

What occurs in the sieve tube elements of a photosynthesising leaf and an actively growing root?

A-LevelBiologyTransport in plantsMay/June 2010

Some soil-borne fungi cause wilting in crop plants by growing within the xylem vessels. Which process will be directly affected by these fungi?

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