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A-LevelBiologyThe mitotic cell cycle9700/12 · Feb/Mar 2025 · Q231 Mark

Telomerase is an enzyme that prevents the shortening of telomeres. It is not present in most normal cells, but is active in an estimated 85% to 95% of human tumour cells. Which statement explains the effect of telomerase on human tumour cells?

ATelomerase triggers a self-destruct process, known as apoptosis, ending the life of the cell.
BTelomerase damages the chromosomes so they become genetically unstable and are unable to replicate and divide.
CTelomerase helps human tumour cells avoid senescence, or cell death, which is usually the expected consequence of repeated cell division.
DTelomerase enables the human tumour cells to divide more rapidly by reducing the time taken for a complete mitotic cell cycle.

✓ Correct answer

C: Telomerase helps human tumour cells avoid senescence, or cell death, which is usually the expected consequence of repeated cell division.

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About this question

Topic
The mitotic cell cycle, A-Level Biology (syllabus 9700). Multiple choice, 1 mark.
Source
A-Level Biology, Feb/Mar 2025 Paper 1 Variant 2, question 23.

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