Fig. 6.1 is an outline diagram showing two stages of aerobic respiration. [Fig. 6.1]
- (a)With reference to Fig. 6.1: name stage X state the precise location of stage Y state the numbered steps in stage Y in which decarboxylation occurs name the type of reaction by which ATP is made during step 3 name substances Q and R.[5]
- (b)Uncontrolled cell division can lead to a cancerous tumour. Many cancer cells break down the amino acid glutamine and convert it to a 5-carbon intermediate compound, which is shown in Fig. 6.1. Suggest how the breakdown of glutamine can lead to the production of ATP in a cancer cell, other than that directly produced during step 3.[2]
This question uses a diagram from the original paper, which isn't shown here. Open the full paper from the past papers archive to see it.
Mark scheme
Marking points from the official mark scheme (May/June 2018). The mark or mark type is shown in brackets.
- [5] link reaction; matrix of mitochondrion ; 2 and 3; substrate-linked phosphorylation; A substrate-level phosphorylation (Q =) NAD and (R=) FAD ;
- [2] reduced, NAD / FAD, to ETC ; A description ref. to oxidative phosphorylation / chemiosmosis ; A description
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