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O-LevelBiologyGenetics & Variation5090/22 · May/June 2015 · Q410 Marks

The dominant allele for the ability to smell the scent of a particular flower is represented by A. The recessive allele, which does not allow a person to smell the scent of the flower, is represented by a.

  1. (a)(i)Using these letters, indicate each of the following: the genotype of a woman who is unable to smell the flower[1]
  2. (a)(ii)the possible alleles found in the gametes of a woman who can smell the flower. ................................................ and ................................................ [2]
  3. (b)Fig. 4.1 represents some alleles on part of the sex chromosomes of a woman and of a man. In the space below, draw these alleles as they might appear in a sperm cell that carries the Y chromosome.[2]
  4. (c)Fig. 4.2 shows how the alleles on one of the chromosomes might appear in a cell taken from somewhere else in the man's body. Allele B shows a mutation. Suggest two possible causes of the mutation.[2]
  5. (d)Mutated alleles such as that shown in Fig. 4.2 are usually recessive. Use your knowledge of genetics to explain why society discourages marriage between closely-related people.[3]

This question uses a diagram from the original paper, which isn't shown here. Open the full paper from the past papers archive to see it.

Mark scheme

Marking points from the official mark scheme (May/June 2015). The mark or mark type is shown in brackets.

  1. [1] (a)(i) aa;
  2. [2] (a)(ii) a/A;
  3. [2] (a)(ii) A;
  4. [2] (b) chromosome with 2 alleles drawn ;
  5. [2] (b) the same two alleles as in Fig. 4.1;
  6. [2] (c) radiation or type named ; e.g. uv, gamma, alpha
  7. [2] (c) chemicals or mutagenic chemical named ; e.g. mustard gas, benzene, tar, etc. Ig ref. to inheritance
  8. [max 3] (d) 1. parents with normal phenotype/appear normal/do not have mutational condition ; A reverse argument throughout
  9. [max 3] (d) 2. heterozygotes/carriers of recessive allele;
  10. [max 3] (d) 3. greater chance (correctly qualified);
  11. [max 3] (d) 4. children + inheriting 2 recessive alleles/being homozygous ; A mutated as being equiv. to recessive throughout
  12. [max 3] (d) 5. suffering from mutational condition; Ig genetic disease

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About this question

Topic
Genetics & Variation, O-Level Biology (syllabus 5090). Structured question, 10 marks.
Source
O-Level Biology, May/June 2015 Paper 2 Variant 2, question 4.

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