A-LevelBiologyGenetic technology9700/12 · Feb/Mar 2021 · Q401 Mark

Why are spleen cells fused with myeloma cells during monoclonal antibody production?

Aso that the antibodies become specific for the necessary antigen

Bso that the resulting hybridoma cells can reproduce indefinitely

Cto allow antibodies that are not specific for the required antigen to be removed

Dto increase the rate of production of antibodies produced by the hybridoma cells

✓ Correct answer

B: so that the resulting hybridoma cells can reproduce indefinitely

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Topic: Genetic technology, A-Level Biology (syllabus 9700). Multiple choice, 1 mark.
Source: A-Level Biology, Feb/Mar 2021 Paper 1 Variant 2, question 40.

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