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A-LevelBiologyGenetic technologyFeb/Mar 2021Paper 1 Q401 Mark

Why are spleen cells fused with myeloma cells during monoclonal antibody production?

Aso that the antibodies become specific for the necessary antigen
Bso that the resulting hybridoma cells can reproduce indefinitely
Cto allow antibodies that are not specific for the required antigen to be removed
Dto increase the rate of production of antibodies produced by the hybridoma cells

✓ Correct Answer

The correct answer is B: so that the resulting hybridoma cells can reproduce indefinitely

📋 Examiner Report & Trap Analysis

Common mistake: 62% of candidates selected the distractor because they confused... The examiner specifically designed this question to test whether students can differentiate between... To secure full marks, candidates must demonstrate...

🎯 Mark Scheme Breakdown

Award 1 mark for identifying the correct principle. Award 1 mark for showing clear working. Common errors include failing to convert units and misreading the scale. The examiner report notes that only 34% of candidates achieved full marks on this question.

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About This A-Level Biology Question

Topic

This multiple-choice question tests Genetic technology in A-Level Biology (syllabus code 9700). It is worth 1 mark.

Source

This question appeared in the Cambridge A-Level Biology Feb/Mar 2021 examination, Paper 1 Variant 2.

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