4 Genetic crosses can be used to investigate patterns of inheritance.
- (a)A mutation in a gene involved in fruit colour in tomato plants, Solanum lycopersicum, results in the production of yellow fruits instead of red fruits. A genetic cross was carried out between a pure breeding plant with a red fruit and a pure breeding plant with a yellow fruit to produce the F1 generation. All offspring plants produced red fruits. The F1 plants were then crossed with each other and the seeds produced were planted to obtain the F2 generation. Construct a genetic diagram to show the cross of the F1 generation that produced this F2 generation. Use the symbols R and r for the alleles.[3]
- (b)A theoretical dihybrid cross involves two genes located on different autosomes. Each gene has two alleles, one dominant and one recessive. A parent, homozygous dominant for both genes, is crossed with a parent that is homozygous recessive for both genes. This produces F1 individuals that are then crossed to produce the F2 generation. State the phenotypic ratio of this dihybrid F2 generation and explain why some of these offspring phenotypes are different from the original parental phenotypes. ratio explanation[3]
Mark scheme
Marking points from the official mark scheme (Oct/Nov 2024). The mark or mark type is shown in brackets.
- parental genotype Rr x Rr
- AND gametes R r R r ;
- offspring genotype RR Rr (Rr) rr ;
- red red red yellow ;
- 1 ratio=9:3:3:1;
- any two from:
- 2 independent / random, assortment ;
- 3 of, homologous chromosomes / bivalents / sister chromatids ;
- 4 stage of meiosis ; e.g. metaphase 1 or metaphase 11
- Ignore ref. to crossing over / recombinants
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