Voltage-gated channels are involved in the generation of an action potential. Fig. 9.1 is a diagram of the voltage-gated channels of sodium ions and potassium ions in the membrane of an axon. The channels are shown in three different states, 1, 2 and 3. [Figure 9.1] Fig. 9.2 is a diagram of different phases of an action potential in an axon. The phases are labelled A, B, C, D, E, F and G. [Figure 9.2]
- (a)Complete Table 9.1 to match each of the listed phases of the action potential with the appropriate state of the voltage-gated channels: 1, 2 or 3.[3]
- (b)Many neurones are surrounded by myelin sheaths. Describe and explain the role of the myelin sheath in the transmission of an action potential.[3]
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Mark scheme
Marking points from the official mark scheme (Oct/Nov 2022). The mark or mark type is shown in brackets.
- [3]
- phase of action potential | state of voltage-gated channels
- A | 2
- C | 1
- E | 3
- F | 3
- G | 2
- 5 correct = 3 marks
- 3/4 correct = 2 marks
- 1/2 correct = 1 mark
- [3] any three from:
- 1 Schwann cells, wrap around the axon / form the myelin sheath;
- 2 insulates (axon) / prevents movement of ions ;
- 3 depolarisation / action potentials, can only occur at nodes (of Ranvier);
- 4 ref. to long(er) local circuits / (nodes are) 1–3 mm apart;
- 5 action potentials, move by saltatory conduction / jump from node to node;
- 6 speed of transmission is, fast(er) / 100 m s-1 ;
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