(a) A neuromuscular junction allows the transmission of an action potential from a motor neurone to a striated muscle fibre, causing it to contract. Fig. 9.1 is a graph of an action potential in a motor neurone. [Figure 9.1] Fig. 9.2 is a graph of an action potential in a striated muscle fibre. [Figure 9.2]
- (a)With reference to Fig. 9.1 and Fig. 9.2, describe the differences between the action potential in a motor neurone and the action potential in a striated muscle fibre.[4]
- (b)There are three phases in the contraction of a striated muscle: latent phase, contraction phase and relaxation phase. The tension in a muscle represents the degree of contraction of its fibres. Fig. 9.3 is a graph of the tension in a striated muscle during the three phases of contraction. [Figure 9.3]
- (b)(i)With reference to Fig. 9.3, explain what is happening in the striated muscle fibre during the latent phase.[3]
- (b)(ii)Suggest why the relaxation phase shows a gradual decrease in muscle tension.[1]
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Mark scheme
Marking points from the official mark scheme (Oct/Nov 2022). The mark or mark type is shown in brackets.
- [4] (a) any four from: motor / neurone 1 resting potential higher ; 2 -70 mV (motor) versus –90 mV (muscle) ; 3 smaller change in membrane potential / smaller depolarisation ; 4 110 mV (motor) versus 130 mV (muscle); 5 action potential / depolarisation, takes less time / is faster ; 6 (action potential) 2.7 ms (motor) versus 4 ms (muscle) or (depolarisation) 1 ms (motor) versus 2 ms (muscle); 7 hyperpolarisation / relative refractory period, occurs ;
- [3] (b)(i) any three from: 1 transverse / T-, tubules depolarised ; 2 Ca2+ diffuse out of sarcoplasmic reticulum ; 3 Ca2+ bind to troponin; 4 tropomyosin, moves from / exposes, binding sites ; 5 for myosin on actin; 6 cross-bridges form / myosin (head) binds to actin;
- [1] (b)(ii) any one from: 1 cross bridges break / myosin heads detach, at different times; 2 AVP;
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