Fig. 6.1 is a photomicrograph of plant cells in stages of the mitotic cell cycle. [Figure 6.1]
- (a)(i)Name the stage of mitosis shown in cell Q.[1]
- (a)(ii)Outline the roles of mitosis in a healthy plant.[2]
- (b)With reference to Fig. 6.2, describe the results and suggest an explanation for the effect of Paclitaxel on the mitotic cell cycle.[4]
This question uses a diagram from the original paper, which isn't shown here. Open the full paper from the past papers archive to see it.
Mark scheme
Marking points from the official mark scheme (Oct/Nov 2022). The mark or mark type is shown in brackets.
- [1] (a)(i) anaphase ;
- [2] (a)(ii) any two from: growth;
- R growth of cells
- repair of tissues (by replacement of cells);
- replacement of, old / dead /damaged / worn out, cells ;
- R repair of cells
- asexual reproduction ;
- production of genetically identical daughter cells ;
- [4] (b) any four from: as concentration of Paclitaxel increases, the ratio of cells in anaphase to those in metaphase reduces / there are a greater proportion of cells in metaphase than in anaphase ;
- as the concentration of Paclitaxel increases, the percentage of cells in mitosis is increasing;
- use of data to support a described trend ;
- idea that as the concentration increases, more cells, stop in metaphase / spend more time in metaphase / fewer cells are able to move into anaphase ;
- suggested mechanism for halt in metaphase ; e.g. centromeres do not divide prevents spindle fibres shortening prevents movement of chromatids to opposite poles (because sister chromatids still held together) cells do not pass the (metaphase) checkpoint
- AVP;
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