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A-LevelBiologyCell membranes and transport9700/22 · Oct/Nov 2017 · Q29 Marks

Triglycerides and phospholipids are types of lipid. Fig. 2.1 shows the structure of one type of phospholipid known as phosphatidylcholine. F1 and F2 are fatty acid residues. [Figure 2.1]

  1. (a)Phospholipase is an enzyme that can break down phospholipids. This enzyme is found in the venom of some insects, such as bees. Bee venom can destroy red blood cells, a condition known as haemolysis. Suggest how bee venom destroys red blood cells.[2]
  2. (b)Compare, stating similarities and differences, the structure of the phosphatidylcholine shown in Fig. 2.1 with the structure of a triglyceride molecule.[4]
  3. (c)Name and describe the cell structure in which the synthesis of triglycerides and other lipids takes place.[3]

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Mark scheme

Marking points from the official mark scheme (Oct/Nov 2017). The mark or mark type is shown in brackets.

  1. [2] two from
  2. cell (surface) membrane / plasma membrane / phospholipid bilayer, damaged / AW ; A phospholipids are in cell surface membrane (and will be broken down by phospholipase)
  3. cell, bursts / lyses / lysis / ruptures ; haemolysis is neutral
  4. cell contents / AW / haemoglobin, leaks out / AW ; I water
  5. [4] allow, fatty acids / fatty acid tails / hydrocarbon chains, for fatty acid residues
  6. both have / similarities (max 3)
  7. glycerol (residue) ;
  8. fatty acids ; I ref. to saturation, R both have, two / three, fatty acids
  9. ester, bonds / linkages ;
  10. C and H and O ;
  11. double bonds ; A both have C=O
  12. differences (max 3)
  13. triglyceride / fat / oil / lipid
  14. no, choline / nitrogen
  15. A no / small / delta, charges
  16. or
  17. phosphatidylcholine / phospholipid
  18. has, choline / nitrogen ;
  19. A choline / nitrogen, ion
  20. A charged / ionic
  21. three fatty acid residues
  22. or one extra fatty acid residue ;
  23. A triglyceride has three ester bonds
  24. or
  25. R if comparison includes phosphatidylcholine and the number of fatty acid residues is incorrect
  26. no, phosphate (group) / phosphorus
  27. A no, phosphoester / phosphodiester bond
  28. or
  29. has phosphate ;
  30. A has phosphoester / phosphodiester bond
  31. [3] smooth endoplasmic reticulum ; A smooth ER RSER R if more than one organelle given R endoplastic
  32. two from
  33. membranous / membranes ; A ref. to vesicles, formed / bud off R envelope / double membrane
  34. tubular; A cisternae but R if described as flattened
  35. fluid filled, channels / sacs ;
  36. not associated with ribosomes ;

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About this question

Topic
Cell membranes and transport, A-Level Biology (syllabus 9700). Structured question, 9 marks.
Source
A-Level Biology, Oct/Nov 2017 Paper 2 Variant 2, question 2.

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