Lysosomes are cell structures that contain enzymes known as acid hydrolases. Fig. 6.1 shows some processes that occur in animal cells. [Figure 6.1]
- (a)Name the cell structures labelled A and E. A ........................................................................................................................................ E ........................................................................................................................................[2]
- (b)State the function of the structures labelled F.[1]
- (c)Name the process by which bacteria are taken into the cell at C.[1]
- (d)With reference to the processes occurring at B and at D in Fig. 6.1, outline the role of acid hydrolases in lysosomes.[3]
- (e)Carrier proteins in the membranes of lysosomes maintain a lower pH than the surrounding cytoplasm by moving hydrogen ions. Suggest how the carrier proteins maintain the lower pH within the lysosomes.[2]
This question uses a diagram from the original paper, which isn't shown here. Open the full paper from the past papers archive to see it.
Mark scheme
Marking points from the official mark scheme (May/June 2021). The mark or mark type is shown in brackets.
- [2] A rough endoplasmic reticulum ;
- E Golgi, body / apparatus / complex;
- [1] transport from, (R)ER / ribosomes, to Golgi ; A from A to E
- A transport from Golgi to, cell surface membrane / phagosome
- A separate, acid hydrolases / enzymes, from, rest of cell / AW
- [1] phagocytosis / endocytosis ;
- [3] any three from
- 1 break down / digest / destroy, bacteria / pathogen(s) ;
- 2 break down / digest / destroy, (worn out / defective / AW), organelles / named organelle (in animal cell) ; A autophagy
- 3 catalyse / speed up, hydrolysis ;
- 4 any two named substrates ;
- e.g. (any named) polysaccharides / proteins / (phospholipids / (named) nucleic acids
- 5 idea that recycle / reuse, biological molecules within cell ;
- 6 (macrophage / phagocyte) cut up to present antigen ;
- [2] moves / pump(s), hydrogen ions / protons, into the lysosome against concentration gradient ;
- active transport / uses ATP / energy from respiration / ref to conformational change of carrier ;
- R if a ref to facilitated diffusion
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