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Edexcel IALMathematicsGeneral Applications8 Marks

The amount of a drug, D mg, in a patient's bloodstream t hours after it has been administered, is given by the formula D = 10e^(-0.2t).

  1. (a)Find the amount of drug in the bloodstream immediately after it has been administered.[1]
  2. (b)Find the time taken for the amount of drug to decrease to 2 mg. Give your answer to 3 significant figures.[4]
  3. (c)Find the rate at which the drug is decreasing 5 hours after it has been administered. Give your answer to 3 significant figures.[3]

Mark scheme

Marking points from the official mark scheme. The mark or mark type is shown in brackets.

  1. (a) B1 for substituting t=0 into D = 10e^(-0.2t) to get D = 10 (mg)
  2. (b) M1 for setting D = 2: 2 = 10e^(-0.2t)
  3. (b) A1 for e^(-0.2t) = 0.2 (o.e. as 1/5)
  4. (b) M1 for taking natural logarithms: -0.2t = ln(0.2)
  5. (b) A1 for t = -ln(0.2) / 0.2 = 8.05 hours (3 s.f.) (accept 8.047... rounded to 3 s.f.)
  6. (c) M1 for differentiating D with respect to t: dD/dt = 10(-0.2)e^(-0.2t) or Akekt form
  7. (c) A1 for dD/dt = -2e^(-0.2t)
  8. (c) A1 for substituting t=5: dD/dt = -2e^(-0.2*5) = -2e^(-1) = -0.736 mg/hour (3 s.f.) (allow 0.736 as the rate of decrease)

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Topic
General Applications, Edexcel IAL Mathematics. Structured question, 8 marks.

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