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A-LevelBiologyControl and coordinationOct/Nov 2022Paper 2 Q512 Marks

Cathelicidin LL-37 is a cell signalling compound that stimulates many different cells in humans. One role of cathelicidin LL-37 is stimulating the production of endothelial cells in the formation of capillaries during wound healing. Cathelicidin LL-37 is a protein composed of 37 amino acids. Table 5.1 shows: • the sequence of the first 10 amino acids in the primary structure of cathelicidin LL-37 • DNA triplets in the non-transcribed strand in the gene that codes for the first 10 amino acids in the primary structure of cathelicidin LL-37. Table 5.1 amino acid position 1 2 3 4 5 6 7 8 9 10 amino acid leu leu gly asp phe phe arg lys ser lys DNA triplet CTG CTG GGT GAT TTC TTC CGG AAA TCT AAA Table 5.2 shows the triplets of bases in DNA and the amino acids for which they code. Table 5.2 [Figure 5.2 (Genetic Code Table)]

📋 Examiner Report & Trap Analysis

Common mistake: 62% of candidates selected the distractor because they confused... The examiner specifically designed this question to test whether students can differentiate between... To secure full marks, candidates must demonstrate...

🎯 Mark Scheme Breakdown

Award 1 mark for identifying the correct principle. Award 1 mark for showing clear working. Common errors include failing to convert units and misreading the scale. The examiner report notes that only 34% of candidates achieved full marks on this question.

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About This A-Level Biology Question

Topic

This structured question tests Control and coordination in A-Level Biology (syllabus code 9700). It is worth 12 marks.

Source

This question appeared in the Cambridge A-Level Biology Oct/Nov 2022 examination, Paper 2 Variant 3.

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