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A-LevelBiologyControl and coordinationOct/Nov 2022Paper 2 Q512 Marks

Cathelicidin LL-37 is a cell signalling compound that stimulates many different cells in humans. One role of cathelicidin LL-37 is stimulating the production of endothelial cells in the formation of capillaries during wound healing. Cathelicidin LL-37 is a protein composed of 37 amino acids. Table 5.1 shows: • the sequence of the first 10 amino acids in the primary structure of cathelicidin LL-37 • DNA triplets in the non-transcribed strand in the gene that codes for the first 10 amino acids in the primary structure of cathelicidin LL-37. Table 5.1 amino acid position 1 2 3 4 5 6 7 8 9 10 amino acid leu leu gly asp phe phe arg lys ser lys DNA triplet CTG CTG GGT GAT TTC TTC CGG AAA TCT AAA Table 5.2 shows the triplets of bases in DNA and the amino acids for which they code. Table 5.2 [Figure 5.2 (Genetic Code Table)]

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About This A-Level Biology Question

This structured question appeared in the Cambridge A-Level Biology (9700) Oct/Nov 2022 examination, Paper 2 Variant 3. It tests the topic of Control and coordination and is worth 12 marks.

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