Cathelicidin LL-37 is a cell signalling compound that stimulates many different cells in humans. One role of cathelicidin LL-37 is stimulating the production of endothelial cells in the formation of capillaries during wound healing. Cathelicidin LL-37 is a protein composed of 37 amino acids. Table 5.1 shows: • the sequence of the first 10 amino acids in the primary structure of cathelicidin LL-37 • DNA triplets in the non-transcribed strand in the gene that codes for the first 10 amino acids in the primary structure of cathelicidin LL-37. Table 5.1 amino acid position 1 2 3 4 5 6 7 8 9 10 amino acid leu leu gly asp phe phe arg lys ser lys DNA triplet CTG CTG GGT GAT TTC TTC CGG AAA TCT AAA Table 5.2 shows the triplets of bases in DNA and the amino acids for which they code. Table 5.2 [Figure 5.2 (Genetic Code Table)]
📋 Examiner Report & Trap Analysis
Common mistake: 62% of candidates selected the distractor because they confused... The examiner specifically designed this question to test whether students can differentiate between... To secure full marks, candidates must demonstrate...
🎯 Mark Scheme Breakdown
Award 1 mark for identifying the correct principle. Award 1 mark for showing clear working. Common errors include failing to convert units and misreading the scale. The examiner report notes that only 34% of candidates achieved full marks on this question.
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