A-LevelBiologyThe mitotic cell cycleOct/Nov 2022Paper 1 Q201 Mark
A gene codes for the production of a protein, p53, that binds to damaged DNA during interphase and prevents its replication. A carcinogen in cigarette smoke mutates the gene coding for the p53 protein, preventing production of the protein. Which statement explains why this mutation may cause cancer?
ACells with no p53 are able to undergo mitosis.
BCells with no p53 replicate their damaged DNA.
CThe carcinogen in cigarette smoke increases the rate of cell division.
DThe mutated p53 causes uncontrolled cell division.
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The correct answer is B. This question tests the candidate's understanding of the mitotic cell cycle within the Biologysyllabus. The examiner's mark scheme requires...
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Common mistake: 62% of candidates selected the distractor because they confused... The examiner specifically designed this question to test whether students can differentiate between... To secure full marks, candidates must demonstrate...
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