A tyrosine kinase receptor (TKR) is a protein complex found in the cell surface membrane of
mammalian cells.
TKR has two components involved in the process of cell signalling:
• a receptor for the signalling molecule (ligand)
• an enzyme that catalyses the transfer of a phosphate group from ATP to an intracellular
protein.
Fig. 3.1 is a diagram to show how TKR is involved in cell signalling.

Q: What topic does this question test?

This question tests Enzymes in A-Level Biology (syllabus code 9700). It is worth 8 marks.

Q: Which exam paper is this question from?

This question appeared in the Cambridge A-Level Biology May/June 2022 examination, Paper 2 Variant 1 (9700_s22_qp_21.pdf).

Question

A tyrosine kinase receptor (TKR) is a protein complex found in the cell surface membrane of
mammalian cells.
TKR has two components involved in the process of cell signalling:
• a receptor for the signalling molecule (ligand)
• an enzyme that catalyses the transfer of a phosphate group from ATP to an intracellular
protein.
Fig. 3.1 is a diagram to show how TKR is involved in cell signalling.

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