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A-LevelBiologyNucleic acids and protein synthesisMay/June 2020Paper 4 Q511 Marks

Yeast cells are unicellular eukaryotes that respond to the presence and absence of different sugars by switching genes on or off. One example of this is summarised in Fig. 5.1. If glucose is present, a sequence of events occurs. • Yeast cells metabolise glucose using constitutively expressed enzymes. • Mig1 transcription factor (A) binds to promoter B. • This stops transcription of gene C. • Production of enzyme D stops. If galactose is present and glucose is absent, a different sequence of events occurs. • The Msn2 transcription factor (E) binds to promoter B. • This activates transcription of gene C. • Enzyme D is produced and helps convert galactose to glucose. Gene F codes for the Mig1 transcription factor, A. Gene G codes for the Msn2 transcription factor, E. [Figure 5.1]

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About This A-Level Biology Question

This structured question appeared in the Cambridge A-Level Biology (9700) May/June 2020 examination, Paper 4 Variant 3. It tests the topic of Nucleic acids and protein synthesis and is worth 11 marks.

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