Yeast cells respond to changes in glucose concentration in their environment by using transcription factors to switch off genes. When glucose is present: Mig1 transcription factors bind to the promoters of five genes Mig1 binding to the promoters stops (represses) transcription of these genes. The genes that are repressed by Mig1 code for five enzymes that allow yeast cells to metabolise the sugar galactose when glucose is absent.
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